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近期暨南大学附属第一医院肿瘤放疗中心治疗师队伍在克服鼻咽癌放射抗性的研究上取得重要进展,相关研究成果“X-ray sensitive selenium-containing Ru complexes sensitize nasopharyngeal carcinoma cells for radio/chemotherapy”发表在国际著名期刊JOURNAL OF MATERIALS CHEMIS...
Over the past decade, the approval of immune checkpoint inhibitors has revolutionized treatment for patients with advanced lung cancer, helping many live longer lives and improving overall survival fo...
肿瘤可以诱发宿主体内多组织器官的系统性病变。原位肿瘤在能够发生转移的同时,还会通过释放可溶性因子、细胞外囊泡与颗粒(EVPs)等破坏机体稳态。近期,康奈尔大学威尔医学院研究人员发现远端肿瘤细胞可以通过分泌的EVPs诱导肝脏代谢功能失调。研究成果发表在《Nature》期刊,论文标题为“Tumour extracellular vesicles and particles dysregulate li...
In the five years since the FDA’s initial approval of chimeric antigen receptor (CAR) T cell therapy, Penn Medicine has gleaned 20 additional approvals related to drugs and techniques to treat or dete...
Every three to five days, all of the cells lining the human intestine are replaced. That constant replenishment of cells helps the intestinal lining withstand the damage caused by food passing through...
The Basser Center for BRCA at Penn Medicine is the first comprehensive center for the research, treatment, and prevention of BRCA-related cancers.
In what may turn out to be a long-missing piece in the puzzle of breast cancer, Harvard Medical School researchers have identified the molecular sparkplug that ignites cases of the disease currently u...
近日,发表在《Nature Communications》上的一项新研究中,来自新加坡国立癌症中心、杜克-新加坡国立大学医学院等多家学术机构的联合研究团队发现了癌症如何逃避免疫系统后在体内转移的机制,并探索了抑制这一危险机制的可能性。该研究对开发癌症治疗的新策略具有重要意义。
以色列特拉维夫大学研究人员发现,一种构成细胞骨架的蛋白质可作为摧毁癌细胞的新靶点。相关论文已发表在美国《科学进展》杂志上。
近日,解放军总医院肿瘤医学部派驻第一医学中心肿瘤中心徐建明主任团队在国际著名期刊《柳叶刀-肿瘤学》(Lancet Oncology)(影响因子54.43)在线发表题为“Tislelizumab plus chemotherapy versus placebo plus chemotherapy as first-line treatment for advanced or metastatic o...
Cancer drugs that stimulate the body’s immune system to attack tumors are a promising way to treat many types of cancer. However, some of these drugs produce too much systemic inflammation when delive...
2023年1月2日,中国医学科学院血液病医院(中国医学科学院血液学研究所)陈俊仁教授、姜尔烈主任、郭晔主任医师和中国科学技术大学第一附属医院孙自敏教授团队联合在American Journal of Hematology《美国血液学杂志》期刊在线发表题为“The Composite Immune Risk Score predicts overall survival after allogene...
A novel cancer therapeutic, combining antibody fragments with molecularly engineered nanoparticles, permanently eradicated gastric cancer in treated mice, a multi-institutional team of researchers fou...
Using an RNA sensor, MIT engineers have designed a new way to trigger cells to turn on a synthetic gene. Their approach could make it possible to create targeted therapies for cancer and other disease...
信号转导和转录激活因子5(STAT5)在某些血液系统恶性肿瘤的发生和进展中起着关键作用,如慢性粒细胞白血病(CML),因而一直以来是一个有吸引力的治疗靶标,但成功靶向STAT5是困难的。近期,密歇根大学的科学家开发了一种选择性小分子降解剂——AK-2292,它可以成功靶向并且去除体内的STAT5蛋白。研究成果发表在《Nature Chemical Biology》期刊,标题为“A selectiv...

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