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Next-gen sequencing identifies non-coding variation disrupting miRNA binding sites in neurological disorders
SCZ ASD
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2017/8/28
Understanding the genetic factors underlying neurodevelopmental and neuropsychiatric disorders is a major challenge given their
prevalence and potential severity for quality of life. While large-scal...
Investigation of the biological basis of human speech and language is being transformed by developments in molecular technologies, including high-throughput genotyping and next-generation sequencing o...
四川大学华西临床医学院精神病学及精神卫生学（医学心理学）课件 应激与心理防御机制。
Language is not isolated from its wider environment: Vocal tract influences on the evolution of speech and language
Biases Language change Linguistic diversity
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2017/8/25
Language is not a purely cultural phenomenon somehow isolated from its wider environment, and we may only understand its origins and evolution by seriously considering its embedding in this environmen...
Left-right asymmetry of maturation rates in human embryonic neural development
gene expression lateralization development
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2017/8/25
Background Left-right asymmetry is a fundamental organizing feature of the human brain, and neuro-psychiatric disorders such as schizophrenia sometimes involve alterations of brain asymmetry. As early...
Language-induced visual and semantic biases in visual search are subject to task requirements
Visual selective attention cognitive control semantics
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2017/8/25
Visual attention is biased by both visual and semantic representations activated by words. We investigated to what extent language-induced visual and semantic biases are subject to task demands. Parti...
Pure linguistic interference during comprehension of competing speech signals
competing speech signals 4-band noise-vocoded sentences
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2017/8/25
Speech-in-speech perception can be challenging because the processing of competing acoustic and linguistic information leads to informational masking. Here, a method is proposed to isolate the linguis...
Converging evidence for abstract phonological knowledge in speech processing
talker perception infancy abstraction
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2017/8/25
The perceptual processing of speech is a constant interplay of multiple competing albeit convergent processes: acoustic input vs. higher-level representations, universal mechanisms vs. language-specif...
Drift, selection, or migration? Processes affecting genetic differentiation and variation along a latitudinal gradient in an amphibian
Genetic drift Natural selection Major histocompatibility complex
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2017/8/25
Past events like fluctuations in population size and post-glacial colonization processes may influence the relative importance of genetic drift, migration and selection when determining the present da...
Disentangling stimulus plausibility and contextual congruency: Electro-physiological evidence for differential cognitive dynamics
Event plausibility Contextual congruency Cross-modal verification
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2017/8/25
Expectancy mechanisms are routinely used by the cognitive system in stimulus processing and in anticipation of appropriate responses. Electrophysiology research has documented negative shifts of brain...
Early development of abstract language knowledge: Evidence from perception-production transfer of birth-language memory
phonological acquisition international adoptees retention of early knowledge
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2017/8/25
Children adopted early in life into another linguistic community typically forget their birth language but retain, unaware, relevant linguistic knowledge that may facilitate (re)learning of birth-lang...
Early phonology revealed by international adoptees' birth language retention
language acquisition adoption phonology
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2017/8/25
Until at least 6 mo of age, infants show good discrimination for familiar phonetic contrasts (i.e., those heard in the environmental language) and contrasts that are unfamiliar. Adult-like discriminat...
Next-generation DNA sequencing identifies novel gene variants and pathways involved in specific language impairment
ERC1 GRIN2A SRPX2
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2017/8/25
A significant proportion of children have unexplained problems acquiring proficient linguistic skills despite adequate intelligence and opportunity. Developmental language disorders are highly heritab...
The development of children's ability to track and predict turn structure in conversation
Turn taking Conversation Development
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2017/8/25
Children begin developing turn-taking skills in infancy but take several years to fluidly integrate their growing knowledge of language into their turn-taking behavior. In two eye-tracking experiments...
Association analysis of dyslexia candidate genes in a Dutch longitudinal sample
SNPs dyslexia candidate genes
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2017/8/25
Dyslexia is a common specific learning disability with a substantive genetic component. Several candidate genes have been proposed to be implicated in dyslexia susceptibility, such as DYX1C1, ROBO1, K...