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目的:建立大鼠正糖钳实验技术。方法:用回归分析和相对标准偏差评价血糖仪的可行性;采用706代血浆作为载体溶液配制胰岛素输注液;改变胰岛素输注速率或葡萄糖输注速率,观察血糖的变化速率。结果:血糖仪相关性好,且精密度高,可满足实验要求;用706代血浆配制胰岛素输注液可满足实验要求;稳态血糖可控制在基础血糖±0.2 mmol.L-1; 血糖对葡萄糖输注速率比对胰岛素输注速率更敏感。结论:首次在国内成功建...
应激致“肾虚”动物模型介绍     应激  肾虚  动物模型       < 2010/1/8
应激致“肾虚”动物模型介绍。
本文报告用小剂量链脲霉素(25 mg/kg)给雌性大鼠静脉注射,使大鼠糖耐量异常,然后加喂高热量食物,引起动物肥胖,饲养8或18周,可形成类似Ⅱ型糖尿病的肥胖大鼠模型。
Background: Stereologic methods are used to obtain quantitative information about three dimensional structures from histologic sections. The aim of present study was using new and unbiased stereologic...
We have studied the ulcerogenic effect of indomethacin in stretozocin. Induced diabetic rats. Streptozocin (65 mg kg-1) was injected intraperitoneally to male wistar rats. The blood glucose concentrat...
In this investigation wer studied the effect of dopaminergic system on the conflict behavior in rat, using vogel’s test. The related drugs were injected intraperitonealy (IP), and produced the followi...
Background: Diabetes mellitus is a worldwide health problem affecting 1-2% of the population. It is responsible for numerous morbidity and mortality consequences due to vascular events such as hyperte...
目的观察脉冲电磁场(PEMFs)对大鼠骨骼肌急性挫伤后行为学及机械刺激缩足反射阈值(PWMT)的影响,并探讨PEMFs在大鼠骨骼肌急性挫伤早期治疗中的应用。 方法将42只SD大鼠分为PEMFs组、造模对照组和空白对照组,每组14只。PEMFs组和造模对照组采用重物自由落体打击法建立大鼠骨骼肌急性挫伤模型,空白对照组不做任何处理。造模成功后,PEMFs组即刻予以PEMFs干预,频率14 Hz,频率可...
The mechanism by which lead may cause a perturbotion in the nevous system is through the nitric oxide synthase. In this study the effect of lead acetate on the hippocampal constitutive nitric oxide pr...
It has been shown that nitric oxide is a mediator with a major role in pain signaling at the level of dorsal root ganglion neurons of the spinal cord. The main objective of the present study was to el...
Glucoronoxylomannan (GXM) is the most important compound of polysaccharide capsule in Cryptococcus neoformans that causes infection in its recognition as a foreign agent by immune system. Because of i...
Antibodies are a diverse class of glycoproteins that specially bind with antigen and elicit a number of secondary responses in vivo. Most of the applications of antibodies in basic research diagnosis ...
Although measurement of intracranial pressure by noninvasive methods has been suggested, but mainly invasive methods are used for this purpose-Increase in episcleral venous pressure can be expected to...
A general rodent control program was carried out in Bandar Abbas in the Persian Gulf (15 Sep-22 Oct 1984). Researches on the variety of the rodents and their parasites were done and Zincphosphide and ...
While legumes are regarded as good sources of protein they may be poorly digested, so it is useful to determine their digestibility which would give a desirable objective in a breeding programme. In t...

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