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Cholesterol-metabolism study suggests new diagnostic, treatment approach for aggressive prostate cancer（图）
diagnostic prostate cancer
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2014/3/20
WEST LAFAYETTE, Ind. - Researchers have discovered a link between prostate cancer aggressiveness and the accumulation of a compound produced when cholesterol is metabolized in cells, findings that cou...
Leydig cell aging：steroidogenic acute regulatory protein（StAR）and cholesterol side-chain cleavage enzyme
Leydig cell aging protein（StAR） cholesterol side-chain cleavage enzyme
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2008/12/26
Primary points of control in steroidogenesis are the transport of cholesterol from intracellular stores to the inner mitochondrial membrane, and the subsequent conversion of cholesterol to pregnenolon...
Cholesterol inhibitory effects on human sperm-induced acrosome reaction
Cholesterol inhibitory human sperm-induced acrosome reaction
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2008/12/25
Progesterone (P4) is known to induce an acrosome reaction in mammalian sperm in vitro, whereas cholesterol is a major inhibitor of acrosome reaction. This study had three objectives: to study the in...
Cholesterol Transport, Peripheral Benzodiazepine Receptor, and Steroidogenesis in Aging Leydig Cells
Mitochondria steroidogenic acute regulatory protein
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2008/12/3
The cellular mechanisms responsible for age-related decline in the ability of Leydig cells to produce testosterone are not yet fully understood. The decline in testosterone production could result fro...