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Objective. To determine the impact of a vaccine hesitancy learning unit on student knowledge, attitudes, and ability to address vaccine hesitancy and/or refusal. Methods. The learning unit consisted ...
Background: Tuberculosis (TB) is regarded as a health problem worldwide, particularly in developing countries. Mycobacterium tuberculosis (M. tuberculosis) is the cause of this disease. Approximately ...
Infection with human papillomavirus (HPV), the sexually transmitted virus that causes cervical and other types of cancer, can be prevented. A safe and effective vaccine has been approved for both boys...
Background: Tuberculosis has been announced as a global emergency by World Health Organization and the second infectious agent of mortality worldwide. The general policy in the development of new vacc...
The most effective way of avoiding influenza is through influenza vaccination. However, the vaccine is ineffective in about 25% of the older population. Immunosenescence with advancing age results in ...
From september to december, 2010, we have assessed the frequency and occurrence of adverse events to Pneumo-coccal conjugated 13-valent vaccine (PCV-13) in the Public vaccination program of the munici...
In Uruguay a post pneumococcal conjugate vaccine implementation surveillance of hospitalized children with pneumonia showed an increase of complicated pneumonias, while uncomplicated pneumonias decrea...
Hemozoin, a bio-crystalline substance, is a hemin detoxification by-product of malaria parasites. The role of hemozoin crystals in host immune system modulation by malaria parasites, and how they inte...
Background: Cryptosporidium parvum is a ubiquitous protozoan, which develops within the microvillous membrane of enterocytes in a wide variety of vertebrates, including man. Cryptosporidiosis is an im...
Background: Immunization against diphtheria, tetanus and pertussis (DTP) has long been applied in Iran using whole cell vac­cine. Despite the role of whole cell DTP (DTwP) vaccine in reduction of ...
An interference is observed between whooping-cough antigens and Salk polioc vaccine even if the two components are mixed immediately before use. The phenomenon is more evident when flUlid antigens are...
Background: Dendritic cells (DCs) are the strongest antigen presenting cells (APCs). They can present antigen to T lymphocytes in vivo and in vitro, and induce cytotoxic T lymphocyte (CTL) reactions. ...
Aim: Studies have shown that no booster dose was required at least 10 to 15 years after a primary vaccination for individuals who developed protective anti-hepatitis B surface (anti-HBs) antibodies. I...
Success in cancer immunotherapy depends on the identification and efficient targeting of specific tumor-associated antigens. Two pivotal strategies to prime patients’ immune system against malignant c...
本项目是针对肿瘤血管生成所需要的VEGF因子,构建了表达异源性VEGF因子的DNA质粒载体,注射到体内产生抗肿瘤血管免疫效应,破坏肿瘤血管,以达到阻断肿瘤生长的作用。因绝大部分肿瘤需血管生长,该制剂有可能用于大部分肿瘤的治疗,有广谱作用。该制剂经多种动物试验证明其抗肿瘤效果明显、安全,并且已能大量生产并获得高纯度及稳定的制剂,作为产业化技术上已无障碍。但申报国家一类新药进行产业化还需完成一些动...

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