搜索结果: 61-75 共查到“知识库 医学 COPD”相关记录91条 . 查询时间(0.089 秒)
间歇使用无创呼吸机在COPD合并Ⅱ型呼吸衰竭的临床应用
间歇无创通气 慢性阻塞性肺病 Ⅱ型呼吸衰竭
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2011/11/30
目的：探讨间歇使用无创呼吸机在治疗慢性阻塞性肺疾病(COPD)合并Ⅱ型呼吸衰竭中的作用。方法：48例COPD急性加重并发Ⅱ型呼吸衰竭患者分为观察组(无创呼吸机组)与对照组(常规观察组)各24例，观察两组治疗前后血pH、PaO2、PaCO2变化。结果：经无创呼吸机通气12小时后观察组PaO2明显升高，PaCO2明显降低，pH明显改善，与对照组比较差异均有统计学意义(P<0.05)。结论：无创呼吸机适...
COPD病人急性发作期C反应蛋白与纤维蛋白原变化
肺疾病 慢性阻塞性 C反应蛋白 纤维蛋白原
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2011/11/17
目的 探讨慢性阻塞性肺疾病(COPD)急性发作期病人血清C反应蛋白(CRP)和纤维蛋白原(Fbg)的含量变化及临床意义。方法 采用速率散射比浊法分别检测30例COPD病人急性发作期、缓解期及30例体检者血清CRP、Fbg的含量，同时测定其1 s用力呼气容积占预计值百分数(FEV1%)及动脉血氧分压(PaO2)。结果COPD病人急性发作期及缓解期血清CRP及Fbg水平较对照组均明显升高，差异有显著性...
本研究主要探讨沙美特罗替卡松气雾剂(舒利迭)联合噻托溴铵对重度极重度慢性阻塞性肺病(COPD)患者肺功能和生活质量的改善作用，以期为今后的临床工作提供参考。
射流式雾化吸入对COPD II型呼吸衰竭治疗效果和安全性
Ⅱ型呼吸衰竭 射流式雾化 血气分析
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2011/10/25
射流式雾化吸入是以氧气为驱动力，利用高速氧流量造成的压力直接将液体药物撞击成微小颗粒，使药液雾化并推动雾化后的颗粒进入气道深部的方法[1]。为了解该雾化方法对COPD II型呼吸衰竭患者的影响，我们采用在雾化前后监测血气分析进行对照观察，以评价其在治疗COPD II型呼吸衰竭患者过程中的临床疗效和安全性，现报告如下。
无创机械通气在COPD中的临床应用
无创机械通气 慢性阻塞性肺疾病
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2011/10/11
慢性阻塞性肺疾病(chronic obstructive pulmonary disease, COPD)是一种具有气流受限特征的可以预防和治疗的疾病,气流受限不完全可逆、呈进行性发展,与肺部对香烟烟雾等有害颗粒的异常炎症反应有关。COPD主要累及肺脏,但也可引起全身的不良反应。由于其患病人数多,病死率高,社会经济负担重,已成为一个重要的公共卫生问题。无创正压通气(nonin-vasive pos...
比较长期联合吸入糖皮质激素（ISC）及长效β2-受体激动剂（LABA）与单药吸入糖皮质激素或长效β2-受体激动剂对改善慢性阻塞性肺疾病（COPD）患者肺功能及气道炎症的作用。方法 将60例中度COPD患者随机分为4组：治疗1组吸入沙莫特罗/氟替卡松，治疗2组吸入福莫特罗，治疗3组吸入布地奈德，对照组按需应用氨荼碱、短效β2受体激动剂。分别在治疗前及治疗后3、6、12、24个月检查动脉血气分...
Bronchodilator Efficacy of Single Doses of Indacaterol in Japanese Patients with COPD: A Randomised, Double-Blind, Placebo-Controlled Trial
beta2-agonists bronchodilator COPD efficacy indacaterol
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2010/11/12
In the Japanese COPD population studied, single doses of indacaterol (150, 300, and 600μg) provided sustained 24-h bronchodilation, with onset of action within 5 min post-dose. All doses were well tol...
观察辛伐他汀对慢性阻塞性肺疾病（COPD）大鼠模型炎症因子及其肺组织病理的影响，探讨辛伐他汀在COPD治疗中的抗炎作用及其机制。方法 采用熏香烟加气管内滴入LPS法建立大鼠COPD模型，随机将30只雄性Wistar大鼠分为正常对照组、COPD模型组和辛伐他汀治疗组，治疗组在造模两周后给予辛伐他汀2.5mg/kg灌胃治疗，每天1次，治疗6周后，观察各组大鼠的体质量增长率，肺组织的病理改变，行支气管...
Correlation between Peripheral Blood T-cell Profiles and Clinical and Inflammatory Parameters in Stable COPD
chronic obstructive pulmonary disease correlation exhaled nitric oxide Tc1/Tc2 transfer coefficient
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2010/11/12
There was a significantly increased proportion of IFN-γ-producing and IL-4-producing CD8+ T cells in patients with COPD compared with control subjects (median [IQR] 73.6% [63.9%-80.7%] vs 62.0% [45.6%...
Pharmacological Treatment in Asthma and COPD
asthma bronchodilators COPD inhaled glucocorticosteroids
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2010/11/16
Many lines of previous studies have reported that differences and similarities between bronchial asthma (BA) and chronic obstructive pulmonary disease (COPD). The pathological and physiological abnorm...
Physiological Differences and Similarities in Asthma and COPD -Based on Respiratory Function Testing-
airflow reversibility airway responsiveness diffusion capacity flow-volume curve impulse oscillation system
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2010/11/16
Physiological differences and similarities in asthma and COPD are documented based on respiratory function testing. (1) The airflow reversibility is usually important for the diagnosis of asthma. Howe...
Radiological Approach to Asthma and COPD-The Role of Computed Tomography
airway remodeling asthma chronic obstructive pulmonary disease (COPD) computed tomography (CT) parenchymal lung disease
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2010/11/16
Asthma and chronic obstructive pulmonary disease (COPD) are among the most prevalent lung diseases. In both asthma and COPD, airway inflammation leads to airway remodeling. Parenchyma of the lung is a...
Asthma and COPD are complex diseases with strong genetic and environmental components. These common pulmonary diseases have both different and similar clinical features. Molecular genetic techniques a...
Differences of Inflammatory Mechanisms in Asthma and COPD
bronchomotor tone inflammatory cells nitric oxide oxidative stress tachykinins
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2010/11/16
Bronchial asthma and chronic obstructive pulmonary disease (COPD) are increasing common diseases. The major pathogenesis of both illnesses is chronic inflammation. However, the inflammatory pattern is...