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This study addressed the neural mediation of discriminative avoidance learning, wherein rabbits step in a wheel apparatus in response to an acoustic conditional stimulus, the CS1, to avoid a foot shoc...
The amygdala is critically involved in discriminative avoidance learning. Large lesions of the amygdala block discriminative avoidance learning and abolish cingulothalamic training-induced neuronal ac...
A substantial literature implicates the anterior and mediodorsal (limbic) thalamic nuclei and the reciprocally interconnected areas of cingulate cortex in learning, memory, and attentional processes. ...
Cingulothalamic neurons develop topographic patterns of cue-elicited neuronal activity during discrimination learning. These patterns are context-related and are degraded by hippocampal lesions, sugge...
Contextual information plays a key role in learning and memory. Learned information becomes associated with the context such that the context can cue the relevant memories and behaviors. An extensive ...
Although most observers agree that the hippocampus has a critical role in learning and memory, there remains considerable debate about the precise functional contribution of the hippocampus to these p...
Contextual information plays a critical role in memory. Learned information becomes associated with the learning context and the context can cue the memories and behaviors associated with that context...
To examine the regulation of midbrain dopamine neurons, recordings were obtained from single neurons of freely moving, genetically engineered dopamine-deficient (DD) mice. DD mice were tested without ...
Several recent studies have shown that hippocampal neurons fire during the delay period in between trials and that these firing patterns differ when different behaviors are required, suggesting that t...
Interference is a critical problem for memory systems and a primary cause of retrieval failure. One strategy for minimizing interference is to associate the items to be remembered with the context in ...
Complex cognitive functions, such as learning and memory, arise from the interaction of multiple brain regions that comprise functional circuits and different components of these circuits make unique ...
Prostaglandin E2 (PGE2), is a major prostanoid produced by the activity of cyclooxygenases (COX) in response to various physiological and pathological stimuli. PGE2 exerts its effects by activating fo...
It is believed that the N400 elicited by concepts belonging to Living is larger than N400 to Objects. This is considered as evidence that concepts are organized, in the brain, on the basis of categori...
Self-consciousness is a product of evolution. Few people today disagree with the evolutionary history of humans. But the nature of self-consciousness is still to be explained, and the story of evoluti...
Researchers often use the term “sensitivity ” when theorizing that certain persons may be more readily affected by various influences than others. Through a review of the literature, it is argued that...

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