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The steps in the development of important medical discoveries
rest first on intuition and then on associations of a certain
factor with a disease, followed by scientifically designed experiments.
T...
Effects of fish-oil supplementation on myocardial fatty acids in humans
Fish oils fatty acids n–3 fatty acids dietary fats myocardium humans
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2008/12/12
Background: Increased fish or fish-oil consumption is associated with reduced risk of cardiac mortality, especially sudden death. This benefit putatively arises from the incorporation of the long-chai...
Combining fish-oil supplements with regular aerobic exercise improves body composition and cardiovascular disease risk factors
n–3 Fatty acids body fat flow-mediated dilatation lipids dual-energy X-ray absorptiometry
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2008/12/12
Background: Regular exercise and consuming long-chain n–3 fatty acids (FAs) from fish or fish oil can independently improve cardiovascular and metabolic health, but combining these lifestyle modificat...
-Linolenic acid and fish oil n–3 fatty acids and cardiovascular disease risk
-Linolenic acid fish oil n–3 fatty acids cardiovascular disease risk
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2008/12/12
In evaluating the cardiovascular merits of n–3 fatty acids, Wang et al (1) appropriately sought the best available evidence and used randomized controlled human trials (RCTs) as their benchmark. As th...
Effects of supplementation with fish oil–derived n−3 fatty acids and γ-linolenic acid on circulating plasma lipids and fatty acid profiles in women
lasma lipids fatty
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2016/12/27
Eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and γ-linolenic acid (GLA) have lipid-modifying and antiinflammatory properties. The effects of supplement mixtures of these fatty acids on pla...
Prostaglandin E2 production and T cell function after fish-oil supplementation: response to antioxidant cosupplementation
Fish oil lymphocyte proliferation interleukin 4
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2017/1/4
Prostaglandin E2 (PGE2) inhibits lymphocyte proliferation and the production of interferon-γ (IFN-γ) by peripheral blood mononuclear cells, but the effect of PGE2 on interleukin 4 (IL-4) production is...
The ability of fish oil to suppress tumor necrosis factor α production by peripheral blood mononuclear cells in healthy men is associated with polymorphisms in genes that influence tumor necrosis factor α production
TNF-α production lymphotoxin α genotype fish oil inflammation healthy men peripheral blood mononuclear cells TNF*1 TNF*2 TNFB*1 TNFB*2
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2016/12/19
Background: Tumor necrosis factor α (TNF-α) mediates inflammation. High TNF-α production has adverse effects during disease. Polymorphisms in the TNF-α and lymphotoxin α genes influence TNF-α producti...
Supplementation of postmenopausal women with fish oil rich in eicosapentaenoic acid and docosahexaenoic acid is not associated with greater in vivo lipid peroxidation compared with oils rich in oleate and linoleate as assessed by plasma malondialdehyde and F2-isoprostanes
Postmenopausal women F2-isoprostanes, malondialdehyde thiobarbituric acid–reactive substances
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2016/6/8
Background: Although the replacement of dietary saturated fat
with unsaturated fat has been advocated to reduce the risk of cardiovascular
disease, diets high in polyunsaturated fatty acids
(PUFAs)...
Fish oil and cardiovascular disease: lipids and arterial function
Fish oil n23 fatty acids eicosapentaenoic acid docosahexaenoic acid lipid modification cardiovascular disease coronary heart disease atherogenesis HDL LDL
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2016/6/3
n23 Fatty acids have been shown to modify several
key risk factors for cardiovascular disease. However, it is not
clear whether the apparent protection against cardiovascular disease
is directly re...