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Nmp4 restricts bone marrow osteoprogenitors and parathyroid hormone induced bone formation in healthy and estrogen depleted female mice
Osteoprogenitor Estrogen depletion
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2015/5/21
We have shown that nuclear matrix protein 4 (Nmp4) attenuates the response to intermittent parathyroid hormone (PTH) in healthy and ovariectomized (OVX) female mice using a global knockout of the Nmp4...
Experimental Carcinoma of Esophagus:I - Effect of Nass in the Squamous Epithelium of Esophagus in Rats and Mice
Rats Mice Carcinoma of Esophagus Squamous Epithelium
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2009/12/3
Our experiments were based on the effects of NASS on squamous epithelium layer of the esophagus in rats and mice as well as its effects on the skin of rats. these experiments concluded hyperplastic a...
Taking aim at aggressive cancer cells--Researchers use novel stem-cell method to discover chemical with potency against breast tumors in mice
cancer cells stem-cell method breast tumors mice
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2009/8/18
A team of researchers led by the Whitehead and Broad Institutes has discovered a chemical that works in mice to kill the rare but aggressive cells within breast cancers that have the ability to seed n...
Combination therapy with cell-binding domain,angiogenesis inhibitor and Ca2+ channel blocker in mice metastatic model
Metastasis Cell-binding domain Fibronectin Angiogenesis inhibitor Ca2+ channel blocker
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2009/7/15
Background: In order to prevent tumor metastasis, we investigated more effective inhibition by combination therapy. The competition with native adhesion molecules by cell-binding domain, inhibition of...