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Scientists Enlist Baker’s Yeast to Find New Medicines
Scientists Enlist Baker’s Yeast New Medicines
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2017/9/1
One of the hardest parts in drug discovery is pinning down how a medicine actually works in the body. It took nearly 100 years to uncover the molecular target of aspirin, but even with cutting-edge te...
Plasma lipid changes after supplementation with β-glucan fiber from yeast
b-glucan dietary fiber oat fiber
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2016/6/1
Dietary fiber has been shown to improve blood
lipids.The purpose of this study was to evaluate the effect
on serum lipids of a yeast-derived b-glucan fiber in 15 free-living,
obese, hypercholestero...
Cholesterol-lowering effects of a proprietary Chinese red-yeast-rice dietary supplement
Chinese red yeast rice Monascus purpureus lipid-lowering rice food
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2016/5/30
We examined the cholesterol-lowering effects of a proprietary
Chinese red-yeast-rice supplement in an American population
consuming a diet similar to the American Heart Association Step I diet
usin...
Glycogen is a major energy reserve in most eukaryotes and its rate of synthesis is controlled by glycogen synthase. The activity of eukaryotic glycogen synthase is regulated by the allosteric activato...
Yeast apurinic/apyrimidinic endonuclease Apn1 protects mammalian neuronal cell line from oxidative stress
DNA repair gene therapy
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2014/12/12
Reactive oxygen species (ROS) have been implicated as one of the agents responsible for many neurodegenerative diseases. A critical target for ROS is DNA. Most oxidative stress-induced DNA damage in t...
The yeast 8-oxoguanine DNA glycosylase (Ogg1) contains a DNA deoxyribophosphodiesterase (dRpase) activity
Ogg1 cloning dRpase activity
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2014/12/12
The yeast OGG1 gene was recently cloned and shown to encode a protein that possesses N-glycosylase/AP lyase activities for the repair of oxidatively damaged DNA at sites of 7,8-dihydro-8-oxoguanine (8...
Comparison of Detection of Antibodies with Yeast Lysate Antigens Prepared from Two Isolates of Blastomyces dermatitidis by Two Different Methods: Sensitivity and Specificity Evaluations
Isoelectric Focusing ELISA Blastomycosis Lysate Antigen Antibody Detection
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2013/1/31
Blastomycosis, a systemic fungal disease, caused by the dimorphic fungus Blastomyces dermatitidis, has continually presented clinicians with concerns with regard to laboratory diagnosis and prevention...
Onychomycosis due to the yeast and yeast-like fungi was investigated among the 147 patient who refered to the mycology laboratory of school of public Health during the period of 11 months. The isolate...
Bacterial, fungal and yeast contamination in six brands of irreversible hydrocolloid impression materials
Dental materials Microbiology Infection control
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2009/10/19
This study assessed the level of contamination of six commercially available irreversible hydrocolloids (two containing chlorhexidine) and identified the contamination present in the materials. Petri ...
Technical Approach to Generate Polyclonal Antibodies Against Bacterially Expressed GST-PYK- C: Evaluation of Cross-Reaction and Recognition in Some Mammalian and Yeast Cell Lysates
pyk-2 Central Nervous System Molecular Cloning Gene Fusion Bacterial Proteins Antibody Formation Antibody Specificity Immunochemistry Immunoblot-ting
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2009/7/1
Pyk-2 is a protein tyrosine kinase, highly expressed in human hippocampus, dentate gyrus and olfactory bulb. In this study, polyclonal antibodies against the C-terminal of pyk-2, starting from Pro-759...
Enhanced Enzymatic Activity of Yeast-like Fungi Responsible for Onychomycosis in Renal Transplant Recipients
Enhanced Enzymatic Activity Yeast-like Fungi Responsible Onychomycosis
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2009/4/20
Background: Renal transplant recipients (RTR) are regarded as a group especially predisposed to onychomycosis. The exact mechanism of increased frequency of onychomycosis in RTR is however not fully...
02 July 2007，A University of Queensland researcher is studying yeast with hopes of finding better ways of preventing viruses.Dr Alan Munn, from UQ’s Institute for Molecular Bioscience, said that curre...
Teaching the Basics of Nuclear Receptor Action: A Simple Laboratory Exercise Using the Yeast Two-Hybrid Method
nuclear receptor yeast two-hybrid ligand laboratory experiment teaching
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2018/4/2
Objectives. Nuclear receptors (NRs) are ligand-activated transcription factors that regulate development and cellular differentiation, endocrine functions, and metabolism and transport of nutrients an...