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Sperm immobilizing activity of a synthetic bioactive peptide 20-44 of 37-kDa cationic antimicrobial protein（CAP37）of human neutrophils
Amphipathic peptides antisperm antibodles complement neutrophil granule-associated protein
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2009/2/13
We have previously reported that human sperm coincubated with human peripheral blood neutrophils in the presence of complement (C)-fixing antisperm antibody (ASA)-positive sera are rapidly interna...
Increased expression of a 68-kDa protein in the corpus cavernosum of some men with erectile dysfunction
Erectile dysfunction cavernous body gel electrophoresis structural proteins
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2009/2/13
Erectile dysfunction (ED) may be caused by abnormalities of intracavernous penile structures. In order to investigate whether specific proteins could be identified that might be related to ED, the c...
Secreted products and extracellular matrix from testicular peritubular myoid cells influence androgen-binding protein secretion by Sertoli cells in culture
Cocultures parabiotic cultures dibutyryl cyclic AMP Sertoli cells peritubular myoid cells
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2009/2/13
Metabolic cooperation mediated by secreted factors between Sertoli cells and peritubular myoid cells has been well documented. We have confirmed that factors secreted by peritubular myoid cells mo...
Effect of bovine oviductal estrus-associated protein on the ability of sperm to capacitate and fertilize oocytes
Oviduct culture proteinsecretion oviductal fluid
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2009/2/12
At estrus, an oviduct-specific, estrus-associated glycoprotein (EAP) of molecular weight 85-95,000, is secreted by the oviductal epithelium and found in cannula-derived bovine oviductal fluid (ODF). T...
Immunoreactive parathyroid hormone-related protein is present in human seminal plasma and is of prostate origin
Immunoreactive parathyroid hormone-related protein human seminal plasma
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2009/2/12
Parathyroid hormone-related protein (PTHrP) is a regulatory peptide that has been associated with normal fetal growth and differentiation as well as the regulation of fetal calcium. We recently d...
Atrial natriuretic factor inhibits the phosphorylation of protein kinase C in plasma membrane preparations of cultured Leydig tumor cells
Atrial natriuretic factor protein kinase C Leydig tumor cells cGMP plasma membranes
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2009/2/12
The peptide hormone atrial natriuretic factor (ANF) exerts its effect in a receptor-mediated fashion and the membrane-bound form of guanylate cyclase represents a biologically active ANF receptor;...
Role of nerve growth factor-like protein in the paracrine regulation of prostate growth
protein paracrine regulation prostate growth
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2009/2/11
Prostate cancer is the most commonly diagnosed form of malignant neoplasia in men. Considerable evidence has accumulated suggesting that paracrine interactions between stromal cells and epithelial cel...
Testicular regulation of epididymal protein secretion
Testicular regulation epididymal protein secretion
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2009/2/10
The effects of different androgen and testicular fluid levels on the protein synthesis and secretion of the epididymis of mice and rats were examined. In mice, the in vitro protein synthesis and s...
GnRH-A induced arrest of spermiogenesis in rats is associated with altered androgen binding protein distribution in the testis and epididymis
GnRH-antagonist Sertoli cell spermatogenesis
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2009/2/10
This study examines the effects of a potent gonadotropin releasing hormone (GnRH)-antagonist (GnRH-A, Ac-D[2] Nal1, 4-CL-D Phe2, D-Trp3, D-Arg6, D-Ala10) upon the distribution of androgen binding pr...
Endocytosis of androgen-binding protein, clusterin, and transferrin in the efferent ducts and epididymis of the ram
Testicular proteins uptake excurrent ducts
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2009/2/7
The amount of androgen-binding protein (ABP) in luminal fluid from the central caput epididymidis of the ram, on a per sperm basis, remains the same as that in rete testis fluid (RTF) entering the...
Assignment of the gene for human intra-acrosomal protein SP-10 to the p12----q13 region of chromosome 11
Spermatogenesis testis-specific gene somatic
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2009/2/7
The human sperm antigen SP-10 is a testis-specific, intra-acrosomal protein associated with the membranes of the acrosomal vesicle. The molecule has been designated a "primary vaccine candidate" b...
Stage-specific expression of a protein of the acrosome of baboon sperm during spermiogenesis detected with a monoclonal antibody
Spermatogenesis spermiogenesis acrosome monoclonal antibody
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2009/2/7
A single monoclonal antibody, BSA4, raised against baboon epididymal sperm was used to study the ontogeny of the baboon sperm acrosome region during testicular spermiogenesis. This antibody is not s...
Correlation between changes in rat sperm membrane lipids, protein, and the membrane physical state during epididymal maturation
Electron paramagnetic resonance spectroscopy(EPR) spin label 5-doxyldecane (5-Nb)
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2009/2/7
An enriched plasma membrane fraction was isolated from caput, corpus, and cauda rat spermatozoa and analyzed for lipid and protein content, thermal phase transition temperature using electron para...
Tissue and species specificity of mouse ductus deferens protein
ductus deferens major protein monoclonal antibodies androgens mouse
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2009/2/6
The ductus deferens of the mouse contains a major protein with a molecular weight of 34.5 kd called mouse vas deferens protein (MVDP). Immunofluorescence histochemistry and immunoblotting with monoclo...
Protein kinase C increases 11beta-hydroxysteroid dehydrogenase oxidation and inhibits reduction in rat Leydig cells
Calcium calmodulin glucocorticoid action oxidoreductases
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2008/12/30
Glucocorticoid hormone controls Leydig cell steroidogenic function through a receptor-mediated mechanism. The enzyme 11beta-hydroxysteroid dehydrogenase (11betaHSD) plays an important role in Leydig...