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Effects of a 5 alpha-reductase inhibitor, finasteride, on the developing prostate and testis of a marsupial
Virilization Wolifian duct tammar wallaby androgen dihydrotestosterone
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2009/2/17
This study examines the role of dihydrotestosterone in virilization of the developing male tammar. The onset of prostate differentiation in this marsupial species normally occurs around 25 days po...
Characterization and developmental expression of a testis-specific adenosine deaminase mRNA in the mouse
testis-specific adenosine deaminase mRNA mouse
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2009/2/17
Adenosine is able to alter intracellular cAMP levels and to affect the physiological functions of sperm. It also modulates FSH action through its Gi protein coupled receptors. Adenosine deaminase (A...
Comparison of the response of rat testis and accessory sex organs to treatment with testosterone and the synthetic androgen methyltrienolone（R1881）
Androgens spermatogenesis testis prostate
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2009/2/17
We have studied the ability of the synthetic androgen methyltrienolone (R1881) to maintain testis and accessory organ weights, as compared to the effect of testosterone propionate (TP). In contrast ...
Expression of apolipoprotein E mRNA in the epithelium and interstitium of the testis and the epididymis
Apolipoprotein E mRNA Leydig cells Sertoli cells
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2009/2/17
Apolipoprotein E (apo E) is an important constituent of plasma lipoproteins and is believed to be involved in the regulation of lipid transport and distribution between tissues. The production of ...
Isolation of highly purified type A spermatogonia from prepubertal rat testis
Type A spermatogonia cell separation c-kit cell culture
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2009/2/17
We have developed a new method that allows isolation of highly purified type A spermatogonia from prepubertal rats. The procedure is based on the maximal release of spermatogonia from the seminifero...
Pituitary control of proliferation and differentiation of Leydig cells and their putative precursors in immature hypophysectomized rat testis
Testis rat development Leydig cells steroidogenesis
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2009/2/17
The objective of this study was to determine the effects of pituitary hormones (luteinizing hormone [LH], follicle-stimulating hormone [FSH], growth hormone [GH], and prolactin [PRL]) on interstit...
Ultrastructural observations of spermatogenesis following transplantation of rat testis cells into mouse seminiferous tubules
Testis spermatogenesis transplant rat mouse
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2009/2/17
The testes of busulfan-treated immunodeficient mice receiving seminiferous tubule injections of testis cells from rats were examined by light and electron microscopy. The presence of active rat sper...
Differential expression of clusterin in the testis and epididymis of postnatal and germ cell deficient mice
clusterin epididymis postnatal germ cell deficient mice
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2009/2/16
Clusterin is found in a wide variety of tissues and is expressed in a number of physiological and pathological contexts. It is expressed constitutively in the adult male reproductive tract, specific...
Testosterone autoregulation of its biosynthesis in the rat testis：inhibition of 17 alpha-hydroxylase activity
1 7a-Hydroxylase testosterone autoregulation rat
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2009/2/16
Using the in vitro perfused rat testis, the effects of testosterone (T) on its own biosynthesis, and in particular on the inhibition of specific steroidogenic step(s) in the biosynthetic pathway fro...
Monoaminergic and peptidergic contributions of the superior and the inferior spermatic nerves to the innervation of the testis in the rat
Testicular capsule mesorchium protein gene product9.5 vasoactive intestinal peptide
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2009/2/13
Sections of the rat testis and whole-mounts of the testicular capsule were studied microscopically using the glyoxylic acid-induced fluorescence method, to detect monoamines, and immunohistochemical...
We have previously found the presence of endothelin (ET) receptor and ET-like immunoreactivity in rat testis. We now extend our studies from rat to human testis. We found expression of a specific tr...
Testis factors that may regulate gene expression: evidence from a patient with Kartagener's syndrome
Kartagener’s syndrome infertility sperm ultrastructure flagella
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2009/2/13
Patients with Kartagener's syndrome characteristically have immotile cilia and flagella. Ultrastructural analysis of the efferent ducts of the patient described in this report revealed that the ci...
Age-related increases in basement membrane thickness have been noted in many tissues, including the testis. The current investigation examined the morphology of the basement membrane in the aged B...
Immunocytochemical localization of glutathione S-transferase Yo subunit in the rat testis and epididymis
Immunocytochemical localization glutathione S-transferase Yo subunit rat testis
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2009/2/12
The glutathione S-transferases (GSTs) are a family of isozymes that catalyze the conjugation of glutathione with electrophiles. These proteins exist as homo- or heterodimers and are separated into...
Lipid peroxidation and antioxidant enzyme activities in the rat testis after cigarette smoke inhalation or administration of polychlorinated biphenyls or polychlorinated naphthalenes
Reactive oxygen oxidative stress superoxide dismutase catalase cigarette smoking environmental chemicals
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2009/2/12
Lipid peroxidation products and antioxidant enzyme activities were studied in the rat testis following exposures to cigarette smoke, polychlorinated biphenyls (PCBs), or polychlorinated naphthalen...