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The effects of aging on the seminiferous epithelium and the blood-testis barrier of the Brown Norway rat
seminiferous epithelium blood-testis barrier Brown Norway rat
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2009/2/18
Steroidogenesis and spermatogenesis decrease in aging Brown Norway rats. We therefore hypothesized that there must be accompanying morphological changes taking place in the seminiferous tubules of...
Evidence for catecholaminergic, neuronlike cells in the adult human testis：changes associated with testicular pathologies
catecholaminergic neuronlike cells adult human testis
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2009/2/18
Neuronlike, catecholaminergic cells expressing tyrosine-hydroxylase (TH) have recently been found in the testis of a nonhuman primate species, the rhesus monkey. We examined whether neuronlike cel...
Expression of cyclin-dependent kinase 5 and associated cyclins in Leydig and Sertoli cells of the testis
cyclin-dependent kinase 5 associated cyclins Leydig and Sertoli cells
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2009/2/18
In this study, we examined the expression and subcellular localization of cyclin-dependent kinase 5 (Cdk5), cyclin D1, and cyclin E in Leydig and Sertoli cell lines that were cultured with 7.5, 1....
Unilateral injection of neuropeptide Y decreases blood flow in the injected testis but may also increase blood flow in the contralateral testis
NPY innervation
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2009/2/18
Neuropeptide Y (NPY) receptors have recently been described in intratesticular arterioles, but the role of NPY in testicular blood-flow regulation has not been examined. To explore this, we admin...
Apoptosis pattern elicited by several apoptogenic agents on the seminiferous epithelium of the adult rat testis
Apoptosis pattern apoptogenic agents seminiferous epithelium adult rat testis
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2009/2/17
Spontaneous germ cell death during spermatogenesis is an important event, and the usefulness of the seminiferous epithelium as an in vivo model to study apoptosis has been evidenced. Nevertheless, the...
The effects of aging on the expression of glutathione S-transferases in the testis and epididymis of the Brown Norway rat
glutathione S-transferases epididymis Brown Norway rat
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2009/2/17
Glutathione S-transferases (GSTs), a family of isoenzymes, catalyze the conjugation of glutathione to a variety of electrophiles, and protect cellular constituents from electrophilic and oxidative...
Previous studies in the rat demonstrated that lymph vessels arise from various sites in the testis and then anastomose to form the main lymph trunk toward the testicular artery. Although mice are ...
Round spermatids from prepubertal mouse testis can develop into normal offspring
ICSI genomic imprinting centriole
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2009/2/17
We investigated fertilization and embryo development after intracytoplasmic injection of round spermatids collected from mice before puberty. The rates of normal fertilization, blastocyst formation,...
Distribution of mouse sulfated glycoprotein-1（prosaposin）in the testis and other tissues
Immunoperoxidase staining immunogold labeling
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2009/2/17
Mouse sulfated glycoprotein-1 (SGP-1) is the homologue of rat SGP-1 and human prosaposin. Rat SGP-1 is one of the major secretory products of rat Sertoli cells in culture. Human prosaposin is the pr...
Altered basement membrane synthesis in the testis after tissue injury
Efferent duct ligation gene expression protein synthesis
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2009/2/17
The basement membrane plays an important role in maintaining the structural and functional integrity of tissues. Altered basement membrane structure has been associated with severe functional impair...
Effect of repeated testicular biopsy on testis function and semen quality in dogs
Sperm output sperm motility spermatogenesis
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2009/2/17
The study was designed to quantitatively evaluate the effect of repeated testicular biopsy of avascular areas by the open method on spermatogenesis, semen quality, and sperm output in dogs. After a ...
Mild hypothermia induces apoptosis in rat testis at specific stages of the seminiferous epithelium
Cell death spermatogenesis ferti
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2009/2/17
This study was designed to determine the effects of short episodes of mild hypothermia on cell apoptosis in the testis of the adult rat. Apoptosis was assessed by in situ DNA 3'-end labeling in the ...
The effects of gonadotropin-releasing hormone immunization and recombinant follicle-stimulating hormone on the Leydig cell and macrophage populations of the adult rat testis
Stereology morphometry optical disector leucocytes
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2009/2/17
The objective of this study was to investigate the role of the gonadotropins and, in particular follicle-stimulating hormone (FSH) in maintaining the Leydig cell and macrophage populations of the adul...
Low density lipoprotein receptor-related protein-1 expression in the testis：regulated expression in Sertoli cells
protein-1 testis regulated expression Sertoli cells
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2009/2/17
The low density lipoprotein receptor-related protein (LRP-1) is a multiligand receptor capable of mediating endocytosis of a wide array of ligands that relate to both lipoprotein metabolism and pr...
Differential methylation in steroid 5 alpha-reductase isozyme genes in epididymis, testis, and liver of the adult rat
Gene methylation gene expression androgens dihydrotestosterone eukaryotic adenine methylation
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2009/2/17
DNA methylation has been largely involved in the regulation of tissue-specific gene expression. The aim of the study was to determine the methylation pattern of steroid 5 alpha-reductase genes 1 and 2...