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Ultrastructural observations of spermatogenesis in mice resulting from transplantation of mouse spermatogonia
Testis mouse spermatogenesis electron microscopy
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2009/2/16
The objective of the present study was to provide a morphological characterization of spermatogenesis following germ cell transplantation into the seminiferous tubular lumen of another mouse. The re...
Developmental expression of glutathione peroxidase, catalase, and manganese superoxide dismutase mRNAs during spermatogenesis in the mouse
Antioxidant enzymes gene expression testis translational regulation
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2009/2/16
We have examined in mouse testis the steady-state levels of mRNAs encoding glutathione peroxidase (GSHPx), catalase (CAT), and superoxide dismutase 2 (SOD-2), three enzymes essential for the antio...
Androgen regulation of molecular forms of beta-D-glucuronidase in the mouse epididymis:comparison with liver and kidney
Androgen regulation 3-glucuronidase egasyn mouse epididymis two-dimensional electrophoresis
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2009/2/16
The expression and androgen regulation of beta-glucuronidase molecular forms were examined in mouse epididymis, liver, and kidney. Two-dimensional polyacrylamide gel electrophoresis performed under ...
Mouse epididymal sperm contain active P450 aromatase which decreases as sperm traverse the epididymis
Spermatozoa estrogen efferent ductules cytoplasmic droplet testicular excurrent ducts
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2009/2/16
Recently we reported that mouse germ cells in the testis contain active P450 aromatase (P450arom), the enzyme that converts androgens to estrogens. This finding suggested that germ cells have the ...
Effect of mesenchymal glandular inductors on the growth and cytodifferentiation of neonatal mouse seminal vesicle epithelium
mesenchymal glandular inductors cytodifferentiation neonatal mouse seminal vesicle epithelium
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2009/2/13
To investigate the developmental properties of glandular mesenchymal inductors along the cranial-caudal extent of the developing male urogenital tract, neonatal mouse seminal vesicle epithelium (S...
Entactin ultrastructural immunolocalization in the basal laminae of mouse seminiferous tubules and with only subtle changes following hypophysectomy
Entactin ultrastructural immunolocalization basal laminae of mouse seminiferous tubules subtle changes hypophysectomy
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2009/2/12
While entactin has been recently reported in the mouse seminiferous tubule lamina propria at the light microscope level, the purpose of this paper was twofold: 1) to determine the ultrastructural ...
Neonatal goitrogen treatment increases adult testis size and sperm production in the mouse
Testis propylthiouracil Sertoli cells hypothyroidism
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2009/2/12
Male rats made hypothyroid during neonatal life show unprecedented increases in adult testis size and daily sperm production (DSP). To determine if this effect was unique to the rat or could also ...
Studies on sperm chromatin structure alterations and cytogenetic damage of mouse sperm following in vitro incubation. Studies on in vitro-incubated mouse sperm
sperm chromatin structure alterations cytogenetic damage of mouse sperm
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2009/2/12
Mouse epididymal sperm incubated in Tyrode's T6 fertilization media were analyzed over time for chromosome damage by two methods. First, cytogenetic analysis was done on paternal pronuclei metapha...
Pituitary adenylate cyclase activating polypeptide(PACAP)can cross the vascular component of the blood-testis barrier in the mouse
Influx constants transport peptide T vasoactive intestinal polypeptide
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2009/2/12
Pituitary adenylate cyclase activating polypeptide (PACAP), present in highest concentrations in the hypothalamus and testes, affects the release of LH, FSH, and prolactin, as well as Sertoli cell...
Direct and indirect effects of murine interleukin-2, gamma interferon, and tumor necrosis factor on testosterone synthesis in mouse Leydig cells
murine interleukin-2 gamma interferon tumor necrosis factor testosterone synthesis
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2009/2/11
It was recently observed that treatment of patients with a high dosage of human interleukin (IL-2) resulted in suppression of plasma concentrations of testosterone. A murine model was developed to a...
Oligotriche and quaking gene mutations. Phenotypic effects on mouse spermatogenesis and testicular steroidogenesis
Oligotriche quaking gene mutations Phenotypic effects mouse spermatogenesis testicular steroidogenesis
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2009/2/10
The phenotypic actions of the oligotriche gene mutation on testicular function have not been elucidated, although it is known that male mice homozygous for the mutation are infertile. In the present...
Heterogeneity of adult mouse Leydig cells with different buoyant densities
Heterogeneity adult mouse Leydig cells different buoyant densities
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2009/2/10
The authors investigated the morphologic characteristics and human chorionic gonadotrophin (hCG)-stimulated testosterone production of adult mouse Leydig cells in vitro, which have different buoya...
Human interleukin-1 alpha crosses the blood-testis barriers of the mouse
Cytokine Sertoli cell transport blood-brain barrier germinal cells
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2009/2/10
Interleukin-1 alpha (IL-1 alpha) has been shown to have direct effects on the gonads, affecting steroidal secretion, DNA synthesis by spermatogonia, and the immune function of the testes. It is un...
Experimental cryptorchidism in the adult mouse. III. Qualitative and quantitative electron microscopic morphology of Leydig cells
Experimental cryptorchidism adult mouse Leydig cells
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2009/2/7
The morphology of Leydig cells of control and 28-day-old cryptorchid mice was studied by electron microscopy and stereologic techniques. Leydig cell profiles of control mice were larger in section...
Extracellular calcium and luteinizing hormone effects on 22-hydroxycholesterol used for testosterone production in mouse Leydig cells
Extracellular calcium luteinizing hormone testosterone production mouse Leydig cells
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2009/2/7
The effect of extracellular calcium on testosterone synthesis in response to luteinizing hormone (LH) or 22-hydroxycholesterol (22-OH-C) by isolated adult mouse Leydig cells was studied. Leydig ce...