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人类免疫缺陷病毒(HIV)之间的重组可能导致病毒毒力、耐药性以及传播能力等方面的改变,从而使病毒能够逃脱疫苗、药物或宿主免疫系统的攻击,成为艾滋病无法被攻克的一个重要原因。在重组过程中获得上述生存优势的HIV重组型毒株可能代替某个区域现有的主要流行毒株,成为该区域新的优势流行株。
Penn Study Models How the Immune System Might Evolve to Conquer HIV
Penn Study Models Immune System HIV
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2016/8/1
It has remained frustratingly difficult to develop a vaccine for HIV/AIDS, in part because the virus, once in our bodies, rapidly reproduces and evolves to escape being killed by the immune system.“Th...
The correlates of dietary intake among HIV-positive adults
Diet sociodemographics AIDS HIV
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2016/6/14
Dietary adequacy, as distinct from weight loss,
has not been examined thoroughly in a diverse cohort of HIVinfected
individuals.
Determinants of low birth weight among HIV-infected pregnant women in Tanzania
HIV infection pregnancy low birth weight
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2016/6/14
Low birth weight (LBW) increases the risk of infant
death, but little is known about its causes among HIV-infected
populations in sub-Saharan Africa.
Effect of highly active antiretroviral therapy on fat, lean, and bone mass in HIV-seropositive men and women
lipodystrophy fat redistribution lean body mass
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2016/6/14
Alterations in body composition have been
reported in HIV-positive adults receiving highly active antiretroviral
therapy (HAART), but the magnitude and potential determinants
of these changes are u...
HIV and other predictors of serum folate, serum ferritin, and hemoglobin in pregnancy: a cross-sectional study in Zimbabwe
Hemoglobin ferritin folate
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2016/6/13
Folate and iron status and hemoglobin concentrations
are important to maternal and infant health.
HIV and other predictors of serum β-carotene and retinol in pregnancy: a cross-sectional study in Zimbabwe
Vitamin A retinol reproduction
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2016/6/13
Vitamin A status during pregnancy is important to
maternal and infant health.
Bone mineral content in girls perinatally infected with HIV
Girls HIV infection bone density
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2016/6/13
Early diagnostic efforts and advances in multidrug
therapy have considerably prolonged the survival time of
children infected perinatally with HIV. Despite these advances,
few studies have addresse...
Bioelectrical impedance analysis in HIV-infected patients treated with triple antiretroviral treatment
AIDS anti-HIV agents body weight
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2016/6/1
Triple antiretroviral treatment including protease
inhibitors (PIs) delays the clinical progression of HIV infection
and may thus reduce the risk of malnutrition. However, fat redistribution
(lipod...
Several studies evaluating resting energy expenditure (REE)
in HIV-infected patients have been published. This component of
energy expenditure, when adjusted for differences in body composition,
ha...
Body composition in HIV-infected children: relations with disease progression and survival
prognosis survival cachexia
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2016/5/31
Malnutrition is common in HIV-infected children,
but the body compartment that is most affected has been ill defined.
Fat distribution in HIV-infected patients reporting truncal enlargement quantified by whole-body magnetic resonance imaging
Adipose tissue regional fat distribution nutrition assessment
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2016/5/31
Antiretroviral therapy has improved the prospects
for people infected with HIV, but some develop a syndrome of
profound body habitus and metabolic alterations that include
truncal enlargement.
Relative influences of sex, race, environment, and HIV infection on body composition in adults
Nutritional assessment body composition bioelectrical impedance analysis
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2016/5/30
The factors that control body composition in disease
are uncertain.
通过调查医院就诊患者HIV抗体阳性情况,为医院院内感染与医护人员防护工作提供重要依据。方法 采用化学发光法(CLIA)与胶体金法对2013~2015年入院患者输血前HIV抗体筛查检测,筛查阳性标本送陕西省疾病控制中心用重组免疫印迹法(WB法)进行确诊。结果 化学发光法HIV筛查阳性标本85例,胶体金法筛查阳性标本47例,经重组免疫印迹法最终确证59例,CLIA法阳性符合率69.4%(59/85),...
2015年12月30日,国际学术期刊Journal of Virology 在线发表了中国科学院上海巴斯德研究所王建华课题组最新研究成果(Human mucosal mast cells capture HIV-1 and mediate viral trans-infection of CD4+ T cells),揭示HIV-1黏膜感染(性传播)新机制。