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Decreased Autocrine EGFR Signaling in Metastatic Breast Cancer Cells Inhibits Tumor Growth in Bone and Mammary Fat Pad
autocrine signaling bone marrow cells breast cancer
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2014/11/6
Breast cancer metastasis to bone triggers a vicious cycle of tumor growth linked to osteolysis. Breast cancer cells and osteoblasts express the epidermal growth factor receptor (EGFR) and produce ErbB...
Sonic hedgehog gene-enhanced tissue engineering for bone regeneration
sonic hedgehog gene-enhanced bone regeneration
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2014/11/6
Improved methods of bone regeneration are needed in the craniofacial rehabilitation of patients with significant bone deficits secondary to tumor resection, congenital deformities, and prior to prosth...
Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2−/− mice
podosome organization bone density osteoclast functions
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2014/11/6
The protein tyrosine kinase Pyk2 is highly expressed in osteoclasts, where it is primarily localized in podosomes. Deletion of Pyk2 in mice leads to mild osteopetrosis due to impairment in osteoclast ...
四川大学华西口腔医学院主办的英文学术期刊Bone Research被SCI数据库收录
四川大学华西口腔医学院 英文学术期刊
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2014/10/31
近日，由口腔疾病研究国家重点实验室、华西口腔医院主办的英文学术期刊Bone Research（BR）被Web of Science接收。自2012年创刊以来发表的所有文章，将进入SCI数据库，这是川大华西口腔医学院主办的第二本英文杂志成功被SCI收录。BR将成为连接世界与中国、口腔医学与医学的重要桥梁，为广大研究者提供高水平的学术交流平台。
Engraftment of bone marrow-derived cells after nonlethal radiation in syngeneic C57BL/6 mice
Chimerism Bone marrow-derived cells Nonlethal radiation
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2015/11/24
To study the characteristics of cell engraftment in mice at a lower dose under nonlethal radiated condition.Methods A syngeneic C57BL/6 mouse model, transplanted with 1×107 bone marrow cells and expos...
Alendronate Effect on the Prevention of Bone loss in Early Stages of Ankylosing Spondylitis: A Randomized, Double-Blind, Placebo-Controlled Pilot Study
Spondylitis Ankylosing Bone Density Alendronate
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2015/10/13
Background:: Ankylosing spondylitis (AS) is an inflammatory rheumatic disease that leads to a progressive ankylosis of vertebras and ossification of paravertebral ligaments. Bone loss and osteoporosis...
中国医科大学组织学与胚胎学英文版课件 Cartilage & Bone。
Increased Resistance during Jump Exercise Does Not Enhance Cortical Bone Formation
BONE FORMATION BIOMECHANICS BONE MASS DIAPHYSIS TIBIA
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2017/5/23
This study sought to elucidate the effects of a low- and high-load jump resistance exercise (RE) training protocol on cortical bone of the tibia and femur mid-diaphyses.
Nmp4 restricts bone marrow osteoprogenitors and parathyroid hormone induced bone formation in healthy and estrogen depleted female mice
Osteoprogenitor Estrogen depletion
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2015/5/21
We have shown that nuclear matrix protein 4 (Nmp4) attenuates the response to intermittent parathyroid hormone (PTH) in healthy and ovariectomized (OVX) female mice using a global knockout of the Nmp4...
Exercise to Improve Pediatric Bone and Fat: A Systematic Review and Meta-analysis
BONE MINERAL DENSITY LEAN MASS OBESITY PEDIATRIC PHYSICAL ACTIVITY
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2017/5/19
This study aimed to determine the effects of school-based, bone-focused exercise interventions on bone, fat, and lean mass in children by systematically reviewing and meta-analyzing the literature.
Mild chronic whole body vibration does not affect bone mineral mass or density in young females
bone DXA woman body composition
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2013/10/3
Whole body vibration (WBV) is increasingly being used in several physical therapy settings. In order to evaluate the ability of WBV to affect bone mineral component, thirty-six young (mean age 25.3 ± ...
Atypical Giant Hydatid Cyst at the Thoracic Wall Causing Bone and Soft Tissue Destruction:Report of a Case
Echinococcosis Atypical Thoracic Wall
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2015/9/30
Hydatid cyst is a zoonotic disease that is common in the Mediterranean region. Thoracic wall, rib or extrapulmonary intrathoracic localization of the cysts is very rare. Giant extrapulmonary intrathor...
High Volumes of Resistance Exercise Are Not Required for Greater Bone Mineral Density during Growth
TIBIA, FEMUR DXA THREE-POINT BENDING TEST
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2017/7/14
Purpose: The purpose of this study was to determine the minimum amount of resistance exercise that would stimulate bone formation, via an elevation in bone mineral density (BMD), during the growth per...
The Application of Fat-Suppression MR Pulse Sequence in the Diagnosis of Bone-Joint Disease
Magnetic Resonance Imaging Fat Suppression Sequences Bone Joint
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2013/1/29
Fat-suppression technology of magnetic resonance is very important in clinical practice.This article is written to interpret the principle, advantages/disadvantages and clinical applications of some r...
One-Stage Repair and Reconstruction of Craniomaxillofacial Bone Defects
Craniomaxillofacial Bone Defects Repair and Reconstruction
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2013/1/30
Objective: Severe craniomaxillofacial injuries and craniomaxillofacial tumors can lead to craniomaxillofacial bone defects and deformities. Seriously affect the patients’ appearance and quality of lif...