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目的:了解2011年ACR/EULAR类风湿关节炎(rheumatoid arthritis, RA)缓解标准与其他常用缓解标准的优劣及临床实用性。方法:现场问卷调查门诊或住院的RA患者,使用2011年ACR/EULAR、1981年ACR、DAS28及CDAI四种缓解标准进行评价,了解各缓解标准的缓解率及达到缓解患者的残余疾病活动度(residual disease activity)情况,对相关...
Objectives: Monocytes/macrophages accumulate in the synovial membrane in rheumatoid arthritis and play a key role in disease pathogenesis, contributing to inflammation, cartilage destruction and bone ...
探讨类风湿关节炎(RA)患者股骨和腰椎部位骨密度(BMD)的变化和骨质疏松(OP)的发生情况。方法,采用DEXA法测定120例RA患者和120例正常人的股骨和腰椎部位BMD,详细记录RA患者各临床及实验室指标。
探讨风湿性疾病合并结核病的临床特点。方法 对2007年1月至2010年4月在我院住院的48例风湿性疾病合并结核病患者的临床资料进行回顾分析。结果 ①所有患者均有半年至30年不等的激素治疗史。②单个、两个及两个以上系统存在结核病变分别有8例、34例、6例。③表现为发热、咳嗽的分别75%和66.7%;结核菌素试验阳性率42%;各种标本(痰、尿、胸水)的涂片阳性率则达60.4%,细菌学阳性(包括涂阳培阳...
观察护理干预对风湿性心脏病患者围手术期焦虑心理状态的影响。方法 采用焦虑自评量表(SAS)对80例风湿性心脏瓣膜病变患者在护理干预前、后进行调查。结果 护理干预前患者焦虑人数为46例(57.5%),护理干预后患者焦虑人数为15例(18.7%),干预前后比较,P<0.01,差异有统计学意义;干预前后患者焦虑分值比较,P<0.01,差异有统计学意义。结论 心理护理、信息支持、现身说法、鼓励家属支持、环...
观察柴胡加龙骨牡蛎汤合盐酸氟西汀治疗中风后抑郁症的临床疗效。方法:采用临床随机对照试验方案,选取符合纳入标准的中风后抑郁症患者70例,随机分为治疗组36例和对照组34例,对照组给予内科常规治疗同时口服盐酸氟西汀,治疗组在对照组基础上给予柴胡加龙骨牡蛎汤治疗。观察两组患者的临床疗效,汉密尔顿抑郁量表评分及不良反应情况。结果:治疗组总有效率88.89%与对照组总有效率70.58%,差别有统计学意义(P...
肿瘤坏死因子-α(tumor necrosis factor alpha,TNF-α)是主要组织相容性复合体(major histocompatibility complex,MHC)基因编码的同源三聚体蛋白,TNF-α与其受体结合后可发挥免疫调节作用并参与机体的多种病理生理过程,包括发热、炎症、感染、创伤愈合和肿瘤杀伤。TNF-α是炎症通路中一重要的细胞因子,存在于类风湿关节炎(rheumato...
Progressive Pseudorheumatoid Chondrodysplasia a rare disorders. Signs and symptoms of the disease developed between three and eight years of age. Patients show clinically and radiographically continue...
Wegener’s Granulomatosis is a necrotizing granulomatous vasculitis involving small and medium sized vessels. The syndrome is classically defined as having involvement of kidney, lungs and upper respir...
Different examination have shown that rheumatoid factor is not responsible for false positive reaction (F.P.R.) in Cr. Neoformanse’s free capsular antigen latex agglutination test, whereas high levels...
Experiments wee performed to evaluate the contralateral effect of adjuvant induced mono arthritis. In these experiments Laser Doppler imaging (LDI) was used to investigate changes in blood flow. Adjuv...
Introduction: Rheumatoid arthritis (RA) is a chronic and systemic inflammatory disease of unknown etiology. It is characterized by symmetric joint involvement with progressive deformities. This leads ...
Rheumatoid arthritis is a disease associated with painful joints that affects approximately 1% of the population worldwide, and for which no effective cure is available. It is characterized by chronic...
Rheumatoid arthritis is a disease associated with painful joints that affects approximately 1% of the population worldwide, and for which no effective cure is available. It is characterized by chronic...
Background and aim: The presence of the flexion relaxation phenomenon (FRP) during trunk flexion represents myoelectric silence consistent with increased load sharing of the posterior discoligamentou...

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