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Ateam of researchers led by Harvard and Broad Institute scientists has developed a new drug-delivery system using engineered DNA-free virus-like particles (eVLPs) that is able to edit genes associated...
Despite its minute size, a single cell contains billions of molecules that bustle around and bind to one another, carrying out vital functions. The human genome encodes about 20,000 proteins, most of ...
美国斯坦福大学医学院科学家领导的联合团队开发的一种新的超快速基因组测序方法,可在平均8小时内诊断出罕见遗传疾病,这是标准临床护理领域中几乎闻所未闻的壮举。相关研究论文日前发表在《新英格兰医学杂志》上。
长期以来,基因突变的随机性一直是生物演化理论的基础,然而这个生物学经典观点受到一项新研究的挑战。来自美国加利福尼亚大学戴维斯分校和德国马克斯·普朗克发育生物学研究所的研究人员日前在英国《自然》杂志上发表论文说,他们通过拟南芥实验发现,基因突变并非是随机的,而是以某种对植物有益的方式进行。这一新发现可能会从根本上改变人们对进化的理解,有望帮助科学家培育出更具优良性状的作物,甚至帮助人类开发对抗癌症等...
In Down syndrome, the third copy of chromosome 21 causes a reorganization of the 3D configuration of the entire genome in a key cell type of the developing brain, a new study shows. The resulting disr...
Ateam of researchers led by Harvard and Broad Institute scientists has developed twin prime editing, a new, CRISPR-based gene-editing strategy that enables manipulation of gene-sized chunks of DNA in ...
The versatility of the nervous system comes from not only the diversity of ways in which neurons communicate in circuits, but also their “plasticity,” or ability to change those connections when new i...
半个世纪以来,科学家一直在寻找解决“蛋白质折叠问题”的方法。这是生物学领域的一项重大挑战,难倒了几代科学家。但现在,人工智能(AI)解决了这一问题。据《自然》杂志1日发表的论文,包括美国华盛顿大学、伦斯勒理工学院和哈佛大学的研究人员在内的研究小组描述了一种升级的阿尔法折叠系统,该系统由深度思维(DeepMind)公司开发,会“构想”出具有稳定结构的新蛋白质。
Achewing gum laced with a plant-grown protein serves as a “trap” for the SARS-CoV-2 virus, reducing viral load in saliva and potentially tamping down transmission, according to a new study.
2021年11月17日,国际权威杂志《美国科学院院刊》(Proceedings of the National Academy of Sciences of the United States of America,PNAS)在线刊登了武汉大学信息管理学院青年教师黄颖副教授作为共同通讯作者的评论文章《迈向包容性的人类基因编辑全球治理》(Toward inclusive global governa...
Cut off the head of a three-banded panther worm, and it will grow another — mouth, brain, and all. Cut off its tail, and the same thing happens. Cut it in three pieces, and within eight weeks there’ll...
近期,美国宾夕法尼亚大学的研究团队发现新型的蛋白折叠驱动因子DAXX(Death Domain-associated Protein,DAXX),可以有效控制蛋白质的正确折叠。相关研究在《Nature》发表,题为:DAXX represents a new type of protein-folding enabler。
近期,来自美国加州大学的科研团队研究发现了一种可靶向定植于癌细胞中的工程益生菌,能将肿瘤微环境中的代谢废物转化为L-精氨酸,从而促进T细胞抗肿瘤免疫应答。该研究在《Nature》上发表,题为:Metabolic modulation of tumours with engineered bacteria for immunotherapy。
When Sharif Tabebordbar was a teenager, his father began having trouble walking. Soon, he became wheelchair-bound and was diagnosed with a rare genetic muscle disease.
The cost of DNA sequencing has plummeted at a rate faster than Moore’s Law, opening large markets in the sequencing space. Genomics for cancer care alone is predicted to hit $23 billion by 2025, but s...

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