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Alcohol, vitamin A, and β-carotene: adverse interactions, including hepatotoxicity and carcinogenicity
Ethanol alcohol retinol
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2016/5/31
Isozymes of alcohol and other dehydrogenases
convert ethanol and retinol to their corresponding aldehydes in vitro.
In addition, new pathways of retinol metabolism have been described
in hepatic mi...
Evaluation of the Protective Effect of Silibinin Against Diazinon Induced Hepatotoxicity and Free-Radical Damage in Rat Liver
Diazinon Oxidative Stress Antioxidants Histopathology Liver
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2015/10/22
Background: Diazinon (0,0-Diethyl 0-(1-6-methyl-2-isoprophyl 4 pyrimidinyl) phosphorothioate) (DI) is a very effective organophosphate pesticide, used widely in agriculture. Consequently, data on pois...
Hepatotoxicity of Halogenated Inhalational Anesthetics
Anesthesiology Liver Injury Drug-Induced Inhalation Anesthesia Halothane Sevoflurane
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2015/10/14
Context: Halogenated inhalational anesthetics are currently the most common drugs used for the induction and maintenance of general anesthesia. Postoperative hepatic injury has been reported after exp...
Anti-tuberculosis drugs related hepatotoxicity;incidence,risk factors,pattern of changes in liver enzymes and outcome
Anti-tuberculosis drugs related hepatotoxicity incidence risk factors pattern of changes liver enzymes outcome
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2009/12/3
Background and the purpose of the study: Tuberculosis is a curable disease if diagnosed and treated properly with anti-tuberculosis drugs. These drugs can cause severe adverse reactions including hepa...
A Rare Side Effect of Metformin: Metformin-Induced Hepatotoxicity
Metformin metformin-associated lactic acidosis hepatotoxicity side effect
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2009/6/17
Metformin is an oral hypoglycemic agent that is commonly used in the treatment of type 2 diabetes mellitus. While metformin-associated metabolic acidosis is a widely recognized side effect of this dru...
Inhibition of Endotoxin-Induced Hepatotoxicity by Melatonin in Rats
endotoxin liver melatonin necrosis oxidative stress tumor necrosis factor α
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2009/4/29
Bacterial endotoxin or lipopolysaccharide causes extensive damage to various organs including the liver. This is due to an increased production of tumor necrosis factor α induced- reactive interme...
Hepatoprotective activity of Ficus carica Linn leaf extract against carbon tetrachloride-induced hepatotoxicity in rats
Ficus carica Leaves Hepatoprotective Carbon tetrachloride
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2010/4/20
The methanol extract of the leaves of Ficus carica Linn. (Moraceae) was evaluated for hepatoprotective activity in rats with liver damage induced by carbon tetrachloride. The extract at an oral dose o...