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Effect of maternal high dosages of folic acid supplements on neurocognitive development in children at 4–5 y of age: the prospective birth cohort Infancia y Medio Ambiente (INMA) study
folic acid supplements folate pregnancy periconception period child neurocognitive development
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2018/11/19
Background: The benefits of the use of folic acid supplements (FASs) during the periconception period to prevent neural tube defects and to ensure normal brain development in offspring are well known....
Effect of maternal high dosages of folic acid supplements on neurocognitive development in children at 4–5 y of age: the prospective birth cohort Infancia y Medio Ambiente (INMA) study
folic acid supplements folate pregnancy periconception period child neurocognitive development
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2018/11/16
Background: The benefits of the use of folic acid supplements (FASs) during the periconception period to prevent neural tube defects and to ensure normal brain development in offspring are well known....
Folic acid: the solution for treating asymptomatic hyperuricemia?
Folic acid solution asymptomatic hyperuricemia
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2018/11/13
Among patients with gout, the increased risk of hypertension and cardiovascular diseases has often been attributed to hyperuricemia (1). Further research confirmed that asymptomatic hyperuricemia, whi...
Folic acid therapy reduces serum uric acid in hypertensive patients: a substudy of the China Stroke Primary Prevention Trial (CSPPT)
controlled hyperuricemia olic acid supplementation new-onset hyperuricemia total homocysteine uric acid concentrations
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2018/11/13
Background: The effect of folic acid supplementation on uric acid (UA) concentrations is still inconclusive.
Longitudinal association between fasting blood glucose concentrations and first stroke in hypertensive adults in China: effect of folic acid intervention
Chinese folic acid hyperglycemia hypertension stroke
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2018/11/13
Background: Diabetes is a known risk factor for stroke, but data on its prospective association with first stroke are limited. Folic acid supplementation has been shown to protect against first stroke...
Moderate folic acid supplementation and MTHFD1-synthetase deficiency in mice, a model for the R653Q variant, result in embryonic defects and abnormal placental development
birth defects developmental defects embryo folic acid high folate methylenetetrahydrofolate reductase MTHFD1 placenta
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2018/12/19
Background: Moderately high folic acid intake in pregnant women has led to concerns about deleterious effects on the mother and fetus. Common polymorphisms in folate genes, such as methylenetetrahydro...
Folic acid enrichment of bread does not appear to affect zinc absorption in young women
Folate folic acid fortification, enrichment
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2016/6/14
In several countries cereals are now enriched with
folic acid to reduce the risk of neural tube defects. Human studies
suggest that folic acid interferes with zinc absorption. This
raises concerns ...
Concomitant supplemental vitamin A enhances the response to weekly supplemental iron and folic acid in anemic teenagers in urban Bangladesh
Retinol vitamin A iron
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2016/6/14
Iron deficiency is the most common micronutrient
deficiency and affects > 2 billion persons worldwide, leading to
anemia in >40% of women of reproductive age in the developing
world.
Fortification with low amounts of folic acid makes a significant difference in folate status in young women: implications for the prevention of neural tube defects
Neural tube defects folic acid fortification
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2016/6/1
Mandatory fortification of grain products with folic
acid was introduced recently in the United States, a policy expected
to result in a mean additional intake of 100 mg/d. One way of predicting
th...
Effects of folic acid on homocysteine in persons classified by methylenetetrahydrofolate reductase genotype
folic acid vitamins B-6
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2016/5/31
Woodside et al (1) recently published an interesting study of
the effects of folic acid and vitamins B-6 and B-12 on total plasma
homocysteine (tHcy) concentrations in 132 men stratified for
the co...
Maternal folate status during extended lactation and the effect of supplemental folic acid
Lactation plasma folate erythrocyte folate
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2016/5/30
Folate requirements during lactation are not well
established.
Low-dose folic acid supplementation decreases plasma homocysteine concentrations: a randomized trial
Supplements folic acid folate
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2016/5/27
An elevated plasma total homocysteine
concentration is a risk factor for cardiovascular disease and neural
tube defects. A high daily intake of supplemental folic acid is
known to decrease total ho...
Synthetic folic acid intakes and status in children living in Ireland exposed to voluntary fortification
children Ireland unmetabolized folic acid voluntary folic acid fortification
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2018/11/27
Background: In the context of mandatory and voluntary folic acid fortification, the exposure of children to folic acid has been a focus of concern, particularly regarding the possibility of whether an...
Effect of folic acid supplementation on homocysteine concentration and association with training in handball players
Nutritional status Sport Folic acid
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2015/7/27
Strenuous physical activity can alter the status of folic acid, a vitamin directly associated with
homocysteine (Hcy); alterations in this nutrient are a risk factor for cardiovascular disease. Handb...
Possible Relationship of Folic Acid Supplementation and Improved Flow-Mediated Dilation in Premenopausal, Eumenorrheic Athletic Women
Premenopause regular menstruation endothelial function folate flow-mediated vasodilation
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2015/4/21
The purpose of this study was to determine if six weeks of folic acid supplementation would improve brachial artery endothelial-dependent flow-mediated dilation in eumenorrheic female runners with pre...