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CCR5 on the NK Cells and its Ligand (RANTES) Expressions are Disrupted in South-Eastern Iranian Patients With Chronic Hepatitis B Infection
Chronic HBV Infection CCR5 RANTES NK Cells
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2015/10/12
Background:: CCR5 is a receptor for CCL3 (MIP-1 α), CCL4 (MIP-1 α) and CCL5 (regulated on activation normal T cell expressed and secreted (RANTES)) and play important roles in recruitment of NK cells ...
Prolonged Combination Therapy is More Effective than Monotherapy in Management of Chronic Hepatitis B Patients With Sustained Virological Response:An Experience From a ‘Real-World’ Clinical Setting
Hepatitis B Chronic Combined Modality Therapy Hepatitis Be Antigens
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2015/10/9
Background:: Little is known about the duration of combination therapy for patients with chronic hepatitis B (CHB) and suboptimal response to nucleos(t)ide analogues(NAs) monotherapy.
Effect of Iron-Mediated Oxidative Stress on Insulin Resistance Through the Forkhead Box-Containing Protein O Subfamily-1 (FOXO-1) Pathway in Chronic Hepatitis C
Chronic Hepatitis C Gluconeogenesis Insulin Resistance Iron Metabolism Oxidative Stress
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2013/1/29
Aims: Chronic hepatitis C virus (HCV) infection is often associated with glucose metabolic disorders and iron overload. It has recently been shown that reactive oxygen species (ROS) increase gluconeog...
High Rate of Virological Response to Peginterferon α-2a–Ribavirin Among Non-Cirrhotic Iranian Hemophilia Patients With Chronic Hepatitis C
Hepatitis C Hemophilia A Hemophilia B Peginterferon alfa-2a Ribavirin Iran
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2015/9/28
Background: Hepatitis C is a major reason of morbidity and mortality among hemophilia patients. Although combi-nation therapy with peginterferon (peg-INF) and ribavirin is considered as standard treat...
Detection of HBV DNA in Cerumen and Sera of Hbsag Negative Patients with Chronic Hepatitis B Infection
HBV DNA Cerumen Sera of Hbsag Negative Patients Chronic Hepatitis B Infection
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2015/9/25
Chronic carriers of hepatitis infection are living throughout the world mostly in the South East of Asia.1-5 Recent studies have shown that some HBsAg negative individuals may develop some sort of chr...
EASL Clinical Practice Guidelines:Management of chronic hepatitis B
Hepatitis B virus EASL guidelines Treatment Interferon alpha Nucleoside/nucleotide analogues
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2011/4/2
Our understanding of the natural history of hepatitis B
virus (HBV) infection and the potential for therapy of the
resultant disease has improved. Several new and effective
antiviral agents have be...
Comparison of liver histopathology between chronic hepatitis C patients and chronic hepatitis B and C-coinfected patients
chronic hepatitis coinfection HBV HCV histology
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2011/4/2
Background:
The aim of the present study was to compare the histological characteristics of livers between chronic hepatitis C (CHC) patients with and without hepatitis B virus (HBV) coinfection.
Me...
Clevudine myopathy in patients with chronic hepatitis B
Clevudine Hepatitis B Adverse effects Myopathy
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2011/4/2
Clevudine (L-FMAU) is a thymidine L-nucleoside analogue that was recently introduced for the treatment of chronic
hepatitis B virus infection. Previous studies showed that clevudine has potent and su...
Virological, serological and biochemical outcomes through 3 years of entecavir treatment in nucleoside-naive Chinese chronic hepatitis B patients
Virological biochemical entecavir treatment
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2011/4/2
Hepatitis B virus (HBV) infection has a high prevalence
in China. Entecavir has shown superior efficacy over
lamivudine in Chinese nucleoside-naive chronic hepatitis B
(CHB) patients over 48 weeks,...
Monotherapy versus combination therapy for the treatment of chronic hepatitis B
Monotherapy versus therapy the treatment of chronic hepatitis B
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2011/4/2
Nucleos(t)ide analogues, active against hepatitis B polymerase, suppress viral replication and improve clinical outcome. However, the emergence of drug-resistant mutants can result in treatment failur...
HBeAg seroconversion as an important end point in the treatment of chronic hepatitis B
HBeAg seroconversion in the treatment of chronic hepatitis B
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2011/4/1
During the natural history of chronic hepatitis
B virus (HBV) infection, the loss of serum hepatitis B e
antigen (HBeAg) and the development of anti-HBe antibodies
(HBeAg seroconversion) mark a tra...
Comparison of quality of life in hepatitis B virus carriers versus chronic hepatitis B virus carriers versus the normal population
Inactive hepatitis B infection HRQOL-SF-36 Turkey
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2010/10/14
To compare health related quality of life (HRQOL) in hepatitis B virus (HBV) carriers versus chronic HBV disease carriers versus the normal population. Materials and methods: The study sample consiste...
The predictive role of AST level, prothrombin time, and platelet count in the detection of liver fibrosis in patients with chronic hepatitis C
Chronic hepatitis C fibrosis serum biochemical markers
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2010/1/11
Aim: We aimed to assess the predictive value of a combination some of basic serum biochemical markers for the diagnosis of clinically significant fibrosis in chronic hepatitis C. Materials and methods...
Expression of Fas Antigen and Bcl-2 Protein in Liver Tissues of Patients with Chronic Hepatitis B
Fas antigen Bcl-2 protein chronic hepatitis B
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2009/6/29
The aim of this study was to evaluate the role of apoptosis in chronic hepatitis B, and correlate it with disease severity. We studied the expression of the Fas antigen (FasAg) and Bcl-2 protein in a ...
Prevalence of chronic hepatitis in children with leukemia, 1996-2001: a single center experience
Hepatitis B Hepatitis C Leukemia Lymphoma Children Cancer
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2015/9/9
Background: There is a risk of viral hepatitis for children with leukemia. Both hepatitis B and C virus infections cause major problems in the management of leukemic patients. In this study, we evalua...