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Circadian variations in liver gene expression: Relationships to drug action
Circadian variations liver gene expression drug action
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2009/12/24
Chronopharmacology is an important but under-explored aspect of therapeutics. Rhythmic
variations in biological processes can influence drug action, including pharmacodynamic
responses, due to ci...
On the potential for integrating gene expression and metabolic flux data
Systems biology gene expression metabolic flux modeling
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2009/12/24
Computational strategies, that integrate genomic-level information and metabolic flux data, have improved both prediction of metabolic fluxes and metabolic network identification. Due to the tight int...
Effects of chronic ingestion of catechin-rich green tea on hepatic gene expression of gluconeogenic enzymes in rats
chronic ingestion catechin-rich green tea hepatic gene expression of gluconeogenic enzymes rats
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2009/5/8
Normal rats were given catechin-rich green tea as drinking fluid and the effects on hepatic gene expression were examined. The results of DNA microarray analysis and quantitative real-time reverse t...
DNA microarray analysis of changes in gene expression induced by 1,25-dihydroxyvitamin D3 in human promyelocytic leukemia HL-60 cells
DNA microarray analysis gene expression 1,25-dihydroxyvitamin D3 promyelocytic leukemia HL-60 cells
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2009/3/2
Using a DNA microarray, we analyzed about 16,600 genes for changes in expression associated with the differentiation of human promyelocytic leukemia HL-60 cells induced by 1α,25-dihydroxyvitamin D3 ...
Changes of HCN gene expression and If currents in Nkx2.5-positive cardiomyocytes derived from murine embryonic stem cells during differentiation
HCN gene expression Nkx2.5-positive cardiomyocytes murine embryonic stem cells
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2009/3/2
Changes in the expression of hyperpolarization-activated cyclic nucleotide (HCN)-gated channels and If currents during the differentiation of embryonic stem cells into cardiac cells remain unknown. ...