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The differential effects of the indazole-carboxylic acid derivative, tolnidamine, on Sertoli cell protein secretion
Indazole-carboxylic acids tolnidamine antispermatogenic agents Sertoli cell
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2009/2/23
The indazole-carboxylic acid derivative tolnidamine (TOL) has marked antispermatogenic activity in rats. Previous morphological and biochemical studies indicate that Sertoli cells are one of the tar...
Leydig cell and extracellular matrix effects on Sertoli cell function：biochemical and morphologic studies
Leydig cell extracellular matrix Sertoli cell function
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2009/2/23
The reciprocal influence between Leydig and Sertoli cells prepared from pig testis were studied by coculture of both types of cells in either plastic dishes or dishes coated with basement membrane...
The action of calcitonin on the TM4 Sertoli cell line and on rat Sertoli cell-enriched cultures
TM4 Sertoli cell line rat Sertoli cell-enriched cultures
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2009/2/23
The effects of synthetic salmon calcitonin on primary Sertoli cell-enriched cultures and on an established cell line (TM4 cells, derived from immature mouse Sertoli cells) were studied. Synthetic ...
Estradiol and plasminogen activator secretion by cultured rat Sertoli cells in response to melanocyte-stimulating hormones
Estradiol and plasminogen activator secretion cultured rat Sertoli cells melanocyte-stimulating hormones
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2009/2/23
Pro-opiomelanocortin-derived peptides, alpha-MSH and beta-endorphin, are synthesized and secreted by Leydig cells, and are believed to have paracrine effects on Sertoli cells in the testis. Peptid...
Incorporation of gossypol and formation of its protein conjugates in mouse transformed Sertoli（TM4）cells
protein conjugates mouse transformed Sertoli（TM4）cells
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2009/2/23
Mitochondria of both mouse transformed Sertoli (TM4) cells and primary-cultured rat and mouse Sertoli cells were shown to be preferentially affected by gossypol (Tanphaichitr et al, 1984). To invest...
Polyamine profiles in rat testis, germ cells and Sertoli cells during testicular maturation
Polyamine profiles rat testis germ cells Sertoli cells
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2009/2/23
Polyamine cellular concentrations (putrescine, spermidine and spermine) in the rat testis and testicular cell types were determined by fluorescence spectroscopy of their dansyl derivatives. A met...
Transferrin secretion in response to different modes of FSH stimulation and cycloheximide in superfused Sertoli cell cultures
Transferrin secretion FSH stimulation cycloheximide superfused Sertoli cell cultures
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2009/2/23
The influence of different modes of FSH stimulation and cycloheximide on transferrin secretion by rat Sertoli cells was investigated using a superfusion culture system. Sertoli cells from 18-day-old...
Effect of germ cells on vectorial secretion of androgen binding protein and transferrin by immature rat Sertoli cells in vitro
germ cells vectorial secretion androgen binding protein transferrin immature rat Sertoli cells
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2009/2/23
The influence of germ cells (greater than 85% pachytene spermatocytes) on vectorial secretion of androgen binding protein (ABP) and transferrin by immature rat Sertoli cells was investigated using t...
Inhibition of ornithine decarboxylase activity by follicle stimulating hormone in primary culture of rat Sertoli cells
ornithine decarboxylase follicle stimulating
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2009/2/23
The effect of follicle stimulating hormone on the activity of ornithine decarboxylase (ODC) was determined in primary culture of rat Sertoli cells. Three different FSH preparations (NIH oFSH-S-15, S...
Tonic inhibition of adenylate cyclase in cultured hamster Sertoli cells
cAMP hamster Sertoli cell adenylate cyclase culture pertussis toxin
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2009/2/23
Sertoli cells cultured from immature hamsters respond to FSH with a dose-related increase in cAMP accumulation. Pertussis toxin acts synergistically with FSH to stimulate cAMP accumulation. This eff...
Cholinergic inhibition of cAMP accumulation in Sertoli cells cultured from immature hamsters
Sertoli cell cAMP muscarinic receptors FSH hamsters testis
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2009/2/23
Acetylcholine inhibits FSH-induced cAMP accumulation in cultured Sertoli cells from immature hamsters. This action of acetylcholine is mimicked by muscarinic cholinergic agonists with a rank order o...
Inhibin production by Sertoli cells during testicular regression in the golden hamster
Inhibin production Sertoli cells testicular regression golden hamster
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2009/2/23
The objective of this study was to determine if testicular regression in the hamster results in changes in Sertoli cell function that reflect altered pituitary function. Inhibin-like activity was me...
Evidence for age-dependent changes in Sertoli cell androgen receptor concentration
age-dependent changes Sertoli cell receptor concentration
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2009/2/23
Cytosol and nuclear receptor concentrations in Sertoli cells isolated from the testes of 15-, 25-, and 35-day-old rats were measured using hydroxylapatite separation procedures. In these cells the m...
Transferrin-mediated transcellular transport of 59Fe across confluent epithelial sheets of Sertoli cells grown in bicameral cell culture chambers
Transferrin-mediated transcellular transport 59Fe Sertoli cells bicameral cell
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2009/2/23
The transferrin-mediated transcellular transport of 59Fe across confluent epithelial sheets of Sertoli cells grown on Millipore filters was investigated. These filters had been impregnated with reco...
Vitamin A modifies the glycopeptide composition of cultured Sertoli cells
Vitamin A modifies glycopeptide composition cultured Sertoli cells
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2009/2/23
Sertoli cells obtained from prepubertal rat testes were cultured in the presence or absence of retinol. Incorporation of monosaccharides and glycopeptide composition of the cells were studied under ...