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Characterization of a TPA-response element in the 5'-flanking region of the androgen receptor gene
Steroid receptor gene expression phorbol esters
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2009/2/18
The androgen receptor (AR) protein is an important transacting factor that is necessary for mediating gene expression of androgen-responsive genes. The expression of the AR gene is regulated by an...
CAG repeat length analysis and mutation screening of the androgen receptor gene in Japanese men with idiopathic azoospermia
Male infertility Kennedy disease sperm production
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2008/12/29
Because androgens are required for normal spermatogenesis, we are investigating abnormalities in the androgen receptor as a possible cause of impaired spermatogenesis in patients with idiopathic mal...
Larger trinucleotide repeat size in the androgen receptor gene of infertile men with extremely severe oligozoospermia
Larger trinucleotide repeat size androgen receptor gene infertile men
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2008/12/26
Androgens are significant regulators of human spermatogenesis. Their action is mediated through the androgen receptor (AR), which binds to the androgen responsive element on DNA and regulates gene tra...
Androgen receptor gene polymorphism and prostate zonal volumes in Australian and Chinese men
Androgen receptor gene polymorphism prostate zonal volumes Australian Chinese men
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2008/12/25
Prostate diseases are age and androgen dependent. The evolution of clinically overt pathology requires decades of exposure to adult male levels of circulating testosterone, but the precise relations...
Association of Long Polyglycine Tracts（GGN Repeats）in Exon 1 of the Androgen Receptor Gene With Cryptorchidism and Penile Hypospadias in Iranian Patients
CAG repeats testicular dysgenesis syndrome molecular diagnosis
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2008/12/24
Hypospadias (a urethral orifice located along the ventral side of the penis) and cryptorchidism (failure of the testes to descend into the scrotal sacs) are the 2 most common congenital malformat...
Male Infertility：No Evidence of Involvement of Androgen Receptor Gene Among Indian Men
Azoospermia oligozoospermia oligoteratozoospermia spermatogenesis
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2008/12/23
Spermatogenesis is collaboratively controlled by testosterone and follicle stimulating hormone. Testosterone and its immediate metabolite dihydrotestosterone affect their roles through the androge...
An Increased CAG Repeat Length in the Androgen Receptor Gene in Azoospermic ICSI Candidates
Assisted reproduction male infertility spermatogenesis
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2008/12/19
The androgen receptor gene has a polymorphic trinucleotide repeat that encodes a polyglutamine tract in its N-terminal transactivation domain. We started this study in order to find out whether a corr...