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清华大学医学院郑撼球课题组在《基因与发育》（Genes ＆ Development）发表合作论文揭示抑制乳腺癌转移的关键因子（图）
清华大学医学院 郑撼球 基因与发育 Genes ＆ Development 论文 揭示抑制乳腺癌 转移 关键因子
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2020/10/22
SNAI2蛋白是SNAIL转录因子家族重要的成员之一。最初在胚胎发育的研究中，发现其对关键发育阶段中细胞的形态改变和细胞迁移发挥重要的作用。随后的研究中发现上皮来源的肿瘤细胞只有在上调以SNAI2为代表的转录因子之后，将自己改变为类似成纤维细胞的“窄长”状，并去除细胞之间的粘连，才能获得强大的组织浸润和迁移能力，从而帮助肿瘤细胞实现离开原位组织并最终发生癌症转移。而在病人预后最差的三阴性乳腺癌中，...
四川大学组织学与胚胎学英文课件 Development of urogenital system
四川大学 组织学与胚胎学 英文课件 Development of urogenital system
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2018/1/23
四川大学组织学与胚胎学英文课件 Development of urogenital system。
四川大学组织学与胚胎学英文课件 Development of cardiovascular system
四川大学 组织学与胚胎学 英文课件 Development of cardiovascular system
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2018/1/23
四川大学组织学与胚胎学英文课件 Development of cardiovascular system。
四川大学组织学与胚胎学英文课件 Development of digestive and respiratory system
四川大学 组织学与胚胎学 英文课件 Development of digestive and respiratory system
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2018/1/23
四川大学组织学与胚胎学英文课件 Development of digestive and respiratory system。
Study:Changing the environment within bone marrow alters blood cell development
Changing the environment bone marrow blood cell development
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2017/3/14
Researchers at the University of Illinois report they can alter blood cell development through the use of biomaterials designed to mimic characteristics of the bone marrow.The findings, reported in th...
LymphTF Database- A Database of Transcription Factor Activity in Lymphocyte Development
LymphTF Database DNA bioinformatics
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2015/5/26
Study of the transcriptional regulation of lymphocyte development has advanced greatly in the past 15 years. Owing to improved techniques and intense interest in the topic, a great many interactions b...
CIS REGULATORY MODULE DISCOVERY IN TH1 CELL DEVELOPMENT
TH1 cell development STAT4 ChIP-on-chip ChIP-Seq
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2015/5/26
Immune response enables the body to resist foreign invasions. The Inflammatory response is an important aspect in the immune response which is articulated by elements such as cytokines, APC, T-cell an...
TRANSGENIC USE OF SMAD7 TO SUPPRESS TGFβ SIGNALING DURING MOUSE DEVELOPMENT
heart development doxycycline inducible
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2015/5/25
Neural crest cells (NCC) are a multipotent population of cells that form at the dorsal region of neural tube, migrate and contribute to a vast array of embryonic structures, including the majority of ...
DIFFERENTIAL ROLE OF PI-3KINASE p85 (α & β) REGULATORY SUBUNITS IN MAST CELL DEVELOPMENT
Cell cycle -- Regulation Enzymes
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2015/5/25
Stem cell factor (SCF) mediated c-Kit signaling, and downstream activation of Phosphatidylinositol-3 Kinase (PI-3K) is critical for multiple biological effects mediated by mast cells. Mast cells expre...
Reconstitution of mouse inner ear sensory development from pluripotent stem cells
Inner ear Pluripotent stem cells Hair cells
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2015/5/21
The inner ear contains specialized sensory epithelia that detect head movements, gravity and sound. Hearing loss and imbalance are primarily caused by degeneration of the mechanosensitive hair cells i...
Prenatal exposure to methyl mercury from fish consumption and polyunsaturated fatty acids: associations with child development at 20 mo of age in an observational study in the Republic of Seychelles
child development maternal fish consumption methyl mercury polyunsaturated fatty acids docosahexaenoic acid arachidonic acid n–6:n–3
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2018/12/24
Background: Fish is a rich source of n–3 polyunsaturated fatty acids (PUFAs) but also contains the neurotoxicant methyl mercury (MeHg). PUFAs may modify the relation between prenatal MeHg exposure and...
OSTOMY COMPLICATIONS AND ASSOCIATED RISK FACTORS: DEVELOPMENT AND TESTING OF TWO INSTRUMENTS
ostomy stoma risk factors complications
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2015/1/19
Complicationsfollowingintestinalostomysurgerycandiminishqualityoflifefor
individualslivingwithanostomy,resultinginphysicalandpsychosociallimitations.Riskfactors
contributingtoostomycomplicationsaren...
中国医科大学组织学与胚胎学英文版课件 Development of the face, neck and limbs
中国医科大学 组织学与胚胎学 英文版 课件 Development of the face, neck and limbs
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2014/9/15
中国医科大学组织学与胚胎学英文版课件 Development of the face, neck and limbs。
中国医科大学组织学与胚胎学英文版课件 Development of Digestive and Respiratory System
中国医科大学 组织学与胚胎学 英文版 课件 Development of Digestive and Respiratory System
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2014/9/15
中国医科大学组织学与胚胎学英文版课件 Development of Digestive and Respiratory System。
Development and Validation of an Objective Balance Error Scoring System
STANDING,BALANCE POSTURAL,CONTROL CONCUSSION,EVALUATION BALANCE,ERROR,SCORING,SYSTEM
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2017/5/24
Limited access to sophisticated technology and the unreliability of simple tools prevent accurate and reliable human standing balance assessments outside research laboratory settings. The goal of this...