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郁金为多基原药材,与莪术、姜黄和片姜黄都来源于姜科姜黄属植物,并且基原之间各有交叉,但在入药部位、炮制方法上各有不同;在传统功效上同为辛、苦味,兼具活血和行气之功,但又有各自的特点和功效倾向。因此,对于这"一组"近缘中药,建立能够反映共同特点和差异性特征的质量评价方法和质量控制体系具有重要意义。在梳理传统文献及总结现代研究报道的基础上,根据中药质量标志物(Q-marker)的概念与核心理论,提出以...
桂枝茯苓方为经典的活血化瘀方,具有改善血液流变性、调节内分泌、抗炎、抗肿瘤、镇痛等作用。古代用于治疗妇人妊娠下血、行经腹痛、产后恶露不尽等症。现代临床其常用于治疗妇科疾病,如子宫肌瘤、卵巢囊肿、痛经、子宫内膜异位症等。对桂枝茯苓方近年来的化学成分、药理作用、临床应用以及质量控制的研究进展进行综述,并在此基础上,基于中药质量标志物(Q-marker)的"五原则"对桂枝茯苓方的Q-marker进行预测...
Analyzing 24-h urine for lithium after consumption of lithium-tagged foods or supplements provides a validated compliance marker but is laborious.
The fatty acid composition of the diet is known to be partially reflected by the fatty acid composition of serum lipids.
Aquasi-experimentaldesignwasundertakentoexplorethepossibilityofutilizing electrodermalactivityasamarkerofintuitivedecisionmakinginnursing.Thisstudy compared11seniorfemalenursingstudentsto10femalenur...
The approach of exploiting highly conserved protein folds and structure in understanding protein function and in designing drugs leads to drugs that are less selective due to association with similar ...
To determine whether red cell distribution width could be used for the assessment of disease activity in patients with inflammatory bowel disease. Materials and methods: A total of 165 patients with i...
CONTEXT: Previous studies suggest that a history of physical or sexual violence is positively associated with a history of sexually transmitted disease (STD). It is important to determine whether abus...
To elucidate the process of metastasis in submucosal gastric cancer (SM-GC), we examined the immunohistochemical expression of matrix metalloproteinases (MMPs: MMP-2, MMP-7, and MMP-9) and tissue inhi...
Signal transducer and activator of transcription (Stat) 3 and p53 integrate upstream signals, and are positive and negative regulators of tumor cell proliferation, respectively. Stat3 and p53 also neg...
We previously reported the presence of type I, and III collagen (Col-I, III) and proliferating cells in human alveolar bone cells (HABCs) three-dimensional (3D) grafts (spheroid). The existence and d...
Rapid advancements in imaging technology have led to remarkable improvements in identification and localization of tumors, ushering the era of high-precision techniques in contemporary radiotherapy p...
We investigated the effect of laughter on salivary endocrinological stress marker chromogranin A (CgA). In saliva samples collected from 11 healthy males before and after watching a comic film or a ...
A patient with hypogonadotropic hypogonadism and anosmia (Kallmann's syndrome) had an associated chromosomal abnormality. Evaluation of the hypothalamic pituitary axis showed undetectable basal LH a...
Azoospermic semen was obtained from 39 vasectomized men and 93 patients consulting for infertility. The latter underwent bioclinical investigations including measurement of plasma FSH and testicular...

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