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The effects of 3-benzoyl-1-methyl-4-phenyl-4 piperidinolhydrochloride (C1), indomethacin, nimesulide and rofecoxib on cyclooxygenase activities in carrageenan-induced paw edema model
3-benzoyl-1-methyl-4-phenyl-4-piperidinol-hydrochloride COX enzymes inflammation
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2010/10/14
The aim of this study was to investigate the effects of 3-benzoyl-1-methyl-4-phenyl-4-piperidinol-hydrochloride (C1), which is a structural and also non-classical isomer of bis Mannich base, bis (3-ar...
The ulcerogenic effect of Indomethacin in diabetic rats
Diabetic rats Gastric ulcer Streptozocin
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2010/1/6
We have studied the ulcerogenic effect of indomethacin in stretozocin. Induced diabetic rats. Streptozocin (65 mg kg-1) was injected intraperitoneally to male wistar rats. The blood glucose concentrat...
Combination of inulin and time dependent polymethacrylates as a coating system to achieve colonic delivery of indomethacin
Colonic drug delivery Indomethacin Inulin Eudragit RS Eudragit RL
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2009/11/26
Background:In the previous study it was shown that films prepared from inulin (In) in combination with Eudragit RS (ERS) and RL (ERL) were susceptible to inulinase. Purpose: The aim of this work was t...
Indomethacin and oxaprozin lower seminal prostaglandin levels but do not influence sperm motion characteristics and serum hormones of young healthy men in a placebo-controlled double-blind trial
seminal prostaglandin levels sperm motion characteristics serum hormones young healthy men
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2009/2/23
To evaluate the influence of indomethacin and oxaprozin on reproductive function in healthy young men, 34 volunteers with normal semen parameters were recruited. In a randomized double-blind design,...
Suppression of the proliferative response of the seminal vesicles to testosterone by inhibitors of prostaglandin synthesis. Testosterone, indomethacin, and proliferation in seminal vesicles
seminal vesicles testosterone prostaglandin synthesis
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2009/2/19
Effects of indomethacin (1.25 mg/kg) and aspirin (20 mg/kg) on testosterone-induced (0.25 mg/rat), and of indomethacin on dihydrotestosterone-induced (0.25 mg/rat) mitotic activity of the seminal ...