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Synthetic chemical fluorescent dyes promise to be useful for many applications in biology. Covalent, targeted labeling, such as with a SNAP-tag, uses synthetic dyes to label specific proteins in vivo ...
Protein kinase dynamics play key roles in regulation of cell differentiation, growth, development and in diverse cell signaling networks. Protein kinase sensors enable visualization of protein kinase ...
Coupling of post-Golgi and endocytic membrane transport ensures that the flow of materials to/from the plasma membrane (PM) is properly balanced. The mechanisms underlying the coordinated trafficking ...
As the main photosynthetic instruments of vascular plants, leaves are crucial and complex plant organs. A strict organization of leaf mesophyll and epidermal cell layers orchestrates photosynthesis an...
贾震宇教授,本科就读于武汉大学生命科学学院生物化学专业。2006年于加州大学河滨分校同时取得统计学硕士和遗传-基因组-生物信息联合学科博士。先后就职于加州大学尔湾分校病理系、阿克伦大学统计系和俄亥俄西北医科大学医学系,从事包括前列腺癌在内的多种疾病的研究以及在生物统计和生物信息学科的教学工作。现受聘为加州大学河滨分校植物科学系数量遗传学教授。贾老师目前的研究工作包括基因组选择方法在作物育种和癌症预...
果实成熟,是指经过一系列生理生化变化而达到最佳食用状态的过程,是果实品质形成的必要前提。然而,随着果实成熟,其对病原菌的抗性也显著降低,导致一系列采后病害的发生,造成巨大的经济损失。传统贮藏保鲜技术通常需要抑制或延缓成熟进程,以牺牲成熟品质为代价,获得较长的货架期,这也导致果实风味和营养物质的严重丧失。因此,如何在有效维持果实成熟品质的同时,增强其对病原菌的抗性是采后生物学研究的重要课题。
多能干细胞(PSC)因其具有自我更新和多向分化潜能,在体外可以长期培养并能进行基因编辑,其在生命科学与医学领域,以及动物育种应用等领域备受青睐。然而,大家畜,如猪,至今没有获得能够进行生殖嵌合、稳定传代、体外长期培养的多能干细胞系。这也是制约大家畜育种的瓶颈。自第一株小鼠胚胎干细胞报道以来,科学家对猪多能干细胞进了30多年的攻关,虽取得了良好的进展,但仍存在急需解决的科学问题。近日,由中国农业大学...
The objective of this study was to explore how retinoic acid (RA) attenuates oxidative injury induced by hydrogen peroxide (H2O2) in bovine mammary epithelial cells (BMEC). Subconfluence BMEC were ran...
Jin L., Yan S., Shi B., Shi H., Guo X., Li J. (2017): Retinoic acid attenuates oxidative injury in bovine mammary epithelial cells induced by hydrogen peroxide. Czech J. Anim. Sci., 62, 539–548. The...
Adipose tissue plays a key role in the development of obesity and diabetes. We previously reported that lignosulfonic acid suppresses the rise in blood glucose levels through the inhibition of α-gluco...
The present study was conducted to examine the effects of retinoic acid (RA) on the synthesis of selenoprotein and the antioxidative indices of bovine mammary epithelial cells (BMEC) in vitro and to e...
The considerable increase in oxygen requirements due to the high metabolic rate of the bovine mammary epithelial cells (BMEC) during lactation results in an augmented production of reactive nitrogen s...
MicroRNAs (miRNAs) are highly conserved, short non-coding RNAs that regulate gene expression at the posttranscriptional level. Although many miRNAs are identified in muscles and muscle cells, their in...
In general, the seminiferous tubule basement membrane (STBM), comprising laminin, collagen IV, perlecan, and entactin, plays an important role in self-renewal and spermatogenesis of spermatogonial ste...
Mammalian target of rapamycin complex 1 (mTORC1) is a central regulator of cell growth and metabolism and is sufficient to induce specific metabolic processes, including de novo lipid biosynthesis. El...

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