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Yen-Jie Lee probes particle collision data for clues to the universe’s origins（图）
粒子碰撞数据 宇宙起源 粒子物理学
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2023/6/9
When Yen-Jie Lee came to MIT as a graduate student in 2006, it was a bit of a culture shock. The aspiring particle physicist had studied physics at National Taiwan University before his career took a ...
新型冠状病毒核酸检测引物和探针序列（Specific primers and probes for detection 2019 novel coronavirus）
新型冠状病 毒核酸检测 探针序列
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2023/3/1
新型冠状病毒核酸检测引物和探针序列
Measuring Electrostatic Fields in Both Hydrogen Bonding and non-Hydrogen Bonding Environments using Carbonyl Vibrational Probes
Ribonucleases Molecular Probes Protein Conformation Vibration Acetophenones Molecular Dynamics Simulation Static Electricity Hydrogen Bonding Solvents
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2016/5/25
Vibrational probes can provide a direct readout of the local electrostatic field in complex molecular environments, such as protein binding sites and enzyme active sites. This information provides an ...
Nitrile Bonds as Infrared Probes of Electrostatics in Ribonuclease S
Nitrile Bonds Infrared Probes Electrostatics Ribonuclease S
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2016/5/25
Three different nitrile-containing amino acids, p-cyanophenylalanine, m-cyanophenylalanine, and S-cyanohomocysteine, have been introduced near the active site of the semisynthetic enzyme ribonuclease ...
Vibrational Stark Effect Probes for Nucleic Acids
ternary complex precipitation europium pyridine-2,6-dicarboxylate fluorescence
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2016/5/24
The vibrational Stark effect (VSE) has proven to be an effective method for the study of electric fields in proteins via the use of infrared probes. To explore the use of VSE in nucleic acids, we inve...
Vibrational Stark Effects Calibrate the Sensitivity of Vibrational Probes for Electric Fields in Proteins
transitional cell carcinoma cDNA microarray molecular markers expression profiling tumor classification
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2016/5/24
Infrared spectroscopy is widely used to probe local environments and dynamics in proteins. The introduction of a unique vibration at a specific site of a protein or more complex assembly offers many a...
19F NMR of Trifluoroacetyl-Labeled Cysteine Mutants of Myoglobin:Structural Probes of Nitric Oxide Bound to the H93G Cavity Mutant
19F NMR Trifluoroacetyl Cysteine Mutants Myoglobin Nitric Oxide H93G Cavity Mutant
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2016/5/23
Nitric oxide (NO) binds to the myoglobin (Mb) cavity mutant, H93G, forming either a 5- or 6-coordinate Fe--NO heme complex. The H93G mutation replaces the proximal histidine of Mb with glycine, allowi...
Engineering Probes to Detect Cholesterol Accessibility on Membranes Using Perfringolysin O
Cholesterol Cholesterol Accessibility Cholesterol Probe Perfringolysin O Cholesterol Depended Cytolysin Pore Forming Toxin
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2014/12/10
Cholesterol is an essential component of mammalian cell membranes and it is important to regulate the structure and function of lipid bilayers. Changes in cholesterol levels are involved in many physi...
Reactive Probes for Manipulating Polyketide Synthases, and Photoreactive Probes for Strained Alkyne Click Chemistry
beta-lactam beta-lactone photochemistry Polyketide
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2014/11/20
Polyketides are a broad class of natural products that have received attention from the scientific community because they are a rich mine of bioactive structures. The common thread that binds the clas...
Development of Miniature Full Flow and Model Pipeline Probes for Testing of Box Core Samples of Surficial Seabed Sediments
box core sampling of seabed sediments cyclic t-bar testing full flow penetrometers intact and remolded undrained shear strength t-bar and ball toroid and model pipeline testing
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2014/11/4
The box corer is a relatively new tool used in the geotechnical community for collection of soft seabed sediments. Miniature full flow and model pipeline probes were developed as tools to characterize...
Relics as probes of galaxy cluster mergers
Cosmology: large-scale structure of Universe – Galaxies: Clusters: general, intracluster medium
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2011/10/12
Galaxy clusters grow by mergers with other clusters and galaxy groups. These mergers create shocks within the intracluster medium (ICM). It is proposed that within the shocks particles can be accelera...
Optimizing future experimental probes of inflation
Optimizing future experimental probes inflation
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2010/12/24
The discovery of many novel realizations of the inflationary universe paradigm has led to a degeneracy problem: many different inflationary Lagrangians generate the same perturbation spectra. Resolvi...
Nuclear spins, magnetic moments and quadrupole moments of Cu isotopes from N = 28 to N = 46: probes for core polarization effects
Nuclear spins magnetic moments quadrupole moments Cu isotopes probes core polarization effects
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2010/12/31
Measurements of the ground-state nuclear spins, magnetic and quadrupole moments of the copper isotopes from 61Cu up to 75Cu are reported. The experiments were performed at the ISOLDE facility, using t...
Optimizing future experimental probes of inflation
Optimizing future experimental probes of inflation
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2010/11/9
The discovery of many novel realizations of the in ationary universe paradigm has led to a degeneracy problem: many di erent in ationary Lagrangians generate the same perturbation spectra.Resolving th...
Static magnetic order of Sr$_{4}$A$_{2}$O$_{6}$Fe$_{2}$As$_{2}$ (A = Sc and V) revealed by local probes
Static magnetic order local probes
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2010/11/19
Static magnetic order of quasi two-dimensional FeAs compounds Sr4A2O6−xFe2As2, with A = Sc
and V, has been detected by 57Fe M¨ossbauer and muon spin relaxation (μSR) spectroscopies. The non-sup...