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A Common Polymorphism of Upstream Transcription Factor 1 Gene is associated with Lipid Profile: A Study in Chinese Type 2 Diabetes Families
dyslipidemia genetic epidemiology single nucleotide polymorphism type 2 diabetes mellitus upstream transcription factor
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2009/10/30
Upstream transcription factor 1 (USF1) is capable of controlling various members in glucose and lipid metabolism pathways. Much evidence suggests that the rs3737787 polymorphism in the USF1 gene may l...
Omental Well-Differentiated Liposarcoma: US, CT and MR Findings
computed tomography liposarcoma magnetic resonance omentum ultrasound
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2009/10/30
Liposarcomas are the most common of sarcoma tumours, they are usually located in the lower limbs, retroperitoneum, or abdominal cavity; up to date, only a few cases of omental liposarcoma with differe...
Classification of BMI control commands from rat's neural signals using extreme learning machine
BMI control rat's neural signals extreme learning machine
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2010/2/25
A recently developed machine learning algorithm referred to as Extreme Learning Machine (ELM) was used to classify machine control commands out of time series of spike trains of ensembles of CA1 hippo...
The development of 3-D, in vitro, endothelial culture models for the study of coronary artery disease
endothelial culture models coronary artery disease
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2010/2/25
The response of the vascular endothelium to wall shear stress plays a central role in the development and progression of atherosclerosis. Current studies have investigated endothelial response using i...
Robust algorithm for arrhythmia classification in ECG using extreme learning machine
Robust algorithm arrhythmia classification ECG extreme learning machine
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2010/2/25
The experimental results of the entire MIT-BIH arrhythmia database demonstrate that the performances of the proposed algorithm are 98.00% in terms of average sensitivity, 97.95% in terms of average sp...
Engineered FADD Induces Apoptosis via an Artificial Death-Inducing Signaling Complex (DISC)
apoptosis FADD biotechnology DISC engineered protein
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2009/10/26
An engineered Fas-associated death domain protein (FADD), 2DEDplusE—made previously by fusing the tandem DEDs of FADD to the E protein of lambda phage-greatly enhances apoptosis-inducing activity in a...
Kinetics of BCR-ABL Transcripts in Imatinib Mesylate treated Chronic Phase CML (CPCML), A Predictor of Response and Progression Free Survival
CML imatinib mesylate molecular responses cytogenetic responses ABL kinase mutations
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2009/10/26
Purpose: To assess the kinetics of molecular response to Imatinib Mesylate (IM) therapy in predicting progression free survival (PFS), sustained hematological, and cytogenetic responses in CPCML. Meth...
Robot-Assisted Laparoscopic Radical Prostatectomy: Technique and Outcomes of 700 Cases
robotic prostatectomy DaVinci prostatectomy radical prostatectomy prostate cancer
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2009/10/26
Background: Robotic prostatectomy techniques are evolving rapidly as the procedure gains popularity and continues to be compared to the gold standard of open retropubic radical prostatectomy. Our obje...
Fluid-structure interaction of a patient-specific abdominal aortic aneurysm treated with an endovascular stent-graft
Fluid-structure interaction a patient-specific abdominal aortic aneurysm an endovascular stent-graft
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2010/2/25
In a patient-specific case peak aneurysm wall stress was reduced by 92%. Such a reduction in aneurysm wall stress may lead to shrinkage of the aneurysm over time. Hence, post-operative stress patterns...
Evaluating the forced oscillation technique in the detection of early smoking-induced respiratory changes
the forced oscillation technique early smoking-induced respiratory changes
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2010/2/25
This study shows that FOT can be used to detect early smoking-induced respiratory changes while these pathologic changes are still potentially reversible. These findings support the use of FOT as a ve...
A Decision Support Framework for Automated Screening of Diabetic Retinopathy
Automated Screening Diabetic Retinopathy
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2009/9/8
The early signs of diabetic retinopathy (DR) are depicted by microaneurysms among other signs. A prompt diagnosis when the disease is at the early stage can help prevent irreversible damages to the di...
Quantitative and O2 Enhanced MRI of the Pathologic Lung: Findings in Emphysema, Fibrosis, and Cystic Fibrosis
the Pathologic Lung Emphysema Cystic Fibrosis
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2009/9/7
Purpose: beyond the pure morphological visual representation, MR imaging offers the possibility to quantify parameters in the healthy, as well as, in pathologic lung parenchyma. Gas exchange is the pr...
a cohesive framework in order to understand the results of qualitatively different measurements in a larger context. Moreover, it is essential to assess the various features of the data quantitatively...
A General Local Reconstruction Approach Based on a Truncated Hilbert Transform
A General Local Reconstruction Approach Truncated Hilbert Transform
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2009/9/7
Exact image reconstruction from limited projection data has been a central topic in the computed tomography (CT) field. In this paper, we present a general region-of-interest/volume-of-interest (ROI/V...
Thalamus Segmentation from Diffusion Tensor Magnetic Resonance Imaging
Thalamus Segmentation Imaging
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2009/9/7
We propose a semi-automatic thalamus and thalamus nuclei segmentation algorithm from Diffusion Tensor Magnetic Resonance Imaging (DT-MRI) based on the mean-shift algorithm. Comparing with existing tha...